XKS1 xylulokinase [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: XKS1
Official Full Name: xylulokinase
Primary source: SGD:S000003426
Locus tag: YGR194C
See related: AllianceGenome:SGD:S000003426; FungiDB:YGR194C; VEuPathDB:YGR194C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables D-xylulokinase activity. Involved in xylulose catabolic process. Located in cytoplasm. Orthologous to human XYLB (xylulokinase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See XKS1 in Genome Data Viewer

Location:: chromosome: VII

Exon count:: 1

Sequence:: Chromosome: VII; NC_001139.9 (886073..887875, complement)

Chromosome VII - NC_001139.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables D-xylulokinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables D-xylulokinase activity	IEA Inferred from Electronic Annotation more info
enables D-xylulokinase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in D-xylose metabolic process	IEA Inferred from Electronic Annotation more info
involved_in carbohydrate phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in xylulose catabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in xylulose metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: xylulokinase

NP_011710.3

EC 2.7.1.17

Xylulokinase; converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001139.9 Reference assembly

Range

886073..887875 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001181323.3 → NP_011710.3 TPA: xylulokinase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_011710.3

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VUX6, P42826

UniProtKB/TrEMBL

B3LI43, G3FCP2, N1P490

Conserved Domains (1) summary

cd07776
Location:22 → 545

FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases