YAT2 carnitine O-acetyltransferase YAT2 [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: YAT2
Official Full Name: carnitine O-acetyltransferase YAT2
Primary source: SGD:S000000826
Locus tag: YER024W
See related: AllianceGenome:SGD:S000000826; FungiDB:YER024W; VEuPathDB:YER024W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables carnitine O-acetyltransferase activity. Involved in alcohol metabolic process and carnitine metabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See YAT2 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 1

Sequence:: Chromosome: V; NC_001137.3 (202192..204963)

Chromosome V - NC_001137.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables carnitine O-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables carnitine O-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables carnitine O-acetyltransferase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in alcohol metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in carnitine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in carnitine metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: carnitine O-acetyltransferase YAT2

NP_010941.1

EC 2.3.1.7

Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001137.3 Reference assembly

Range

202192..204963

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001178915.1 → NP_010941.1 TPA: carnitine O-acetyltransferase YAT2 [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_010941.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D3DLS3, P40017

UniProtKB/TrEMBL

G2WCQ7

Conserved Domains (1) summary

pfam00755
Location:23 → 733

Carn_acyltransf; Choline/Carnitine o-acyltransferase