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    YSF3 U2 snRNP complex subunit YSF3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 1466511, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YSF3
    Official Full Name
    U2 snRNP complex subunit YSF3
    Primary source
    SGD:S000028509
    Locus tag
    YNL138W-A
    See related
    AllianceGenome:SGD:S000028509; FungiDB:YNL138W-A; VEuPathDB:YNL138W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RCP10
    Summary
    Involved in spliceosomal complex assembly. Part of U2 snRNP. Orthologous to human SF3B5 (splicing factor 3b subunit 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YSF3 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    2
    Sequence:
    Chromosome: XIV; NC_001146.8 (366033..366412)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene adenine deaminase Neighboring gene uncharacterized protein Neighboring gene Tho2p Neighboring gene adenylate cyclase-binding protein Neighboring gene mitochondrial 37S ribosomal protein NAM9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Rauhut R, et al. Science, 2016 Sep 23. PMID 27562955
    2. SF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeast. Carrocci TJ, et al. Nucleic Acids Res, 2017 May 5. PMID 28062854, Free PMC Article
    3. Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing. Dziembowski A, et al. EMBO J, 2004 Dec 8. PMID 15565172, Free PMC Article
    4. Interactions of the yeast SF3b splicing factor. Wang Q, et al. Mol Cell Biol, 2005 Dec. PMID 16314500, Free PMC Article
    5. Structural insights into how Prp5 proofreads the pre-mRNA branch site. Zhang Z, et al. Nature, 2021 Aug. PMID 34349264, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spliceosomal complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    U2 snRNP complex subunit YSF3
    NP_878153.1
    • Component of the SF3b subcomplex of the U2 snRNP; essential protein required for splicing and for assembly of SF3b

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      366033..366412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184519.1 → NP_878153.1  TPA: U2 snRNP complex subunit YSF3 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_878153.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W143, P0C074
      UniProtKB/TrEMBL
      A6ZRU4, C8ZG91, G2WLW7
      Conserved Domains (1) summary
      pfam07189
      Location:3 → 73
      SF3b10; Splicing factor 3B subunit 10 (SF3b10)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C074.1

    Gene LinkOut

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