U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RPA49 DNA-directed RNA polymerase I subunit RPA49 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855473, updated on 9-Dec-2024

    Summary

    Official Symbol
    RPA49
    Official Full Name
    DNA-directed RNA polymerase I subunit RPA49
    Primary source
    SGD:S000005192
    Locus tag
    YNL248C
    See related
    AllianceGenome:SGD:S000005192; FungiDB:YNL248C; VEuPathDB:YNL248C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Contributes to RNA polymerase I activity. Involved in transcription elongation by RNA polymerase I. Located in nucleolus. Part of RNA polymerase I complex. Orthologous to human POLR1E (RNA polymerase I subunit E). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See RPA49 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (181361..182608, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene MRX complex DNA-binding subunit Neighboring gene Mpa43p Neighboring gene cysteine--tRNA ligase Neighboring gene Vps75p Neighboring gene U2-type spliceosomal complex subunit CWC25

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to RNA polymerase I activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase I complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of RNA polymerase I complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerase I subunit RPA49
    NP_014151.1
    • RNA polymerase I subunit A49; essential for nucleolar assembly and for high polymerase loading rate; required for nucleolar localization of Rpa34p

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      181361..182608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183086.1NP_014151.1  TPA: DNA-directed RNA polymerase I subunit RPA49 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014151.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0U5, Q01080
      UniProtKB/TrEMBL
      A6ZRJ5, B3LP88, B5VQG1, C7GPB3, C8ZFY9, G2WLL8, N1P524
      Conserved Domains (1) summary
      pfam06870
      Location:33411
      RNA_pol_I_A49; A49-like RNA polymerase I associated factor