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    Tubgcp5 tubulin gamma complex component 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308663, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tubgcp5provided by RGD
    Official Full Name
    tubulin gamma complex component 5provided by RGD
    Primary source
    RGD:1304689
    See related
    EnsemblRapid:ENSRNOG00000011480 AllianceGenome:RGD:1304689
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable gamma-tubulin binding activity and microtubule binding activity. Predicted to contribute to microtubule minus-end binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Predicted to be located in centrosome and cytosol. Predicted to be part of gamma-tubulin ring complex. Orthologous to human TUBGCP5 (tubulin gamma complex component 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 111.2), Heart (RPKM 94.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tubgcp5 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (115772294..115807947)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (106636526..106672175)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (114186853..114222516)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene NIPA magnesium transporter 1 Neighboring gene sialic acid binding Ig-like lectin H Neighboring gene ras homolog family member Q, pseudogene 1 Neighboring gene uncharacterized LOC134483327 Neighboring gene dynein light chain 1, cytoplasmic-like Neighboring gene cytoplasmic FMR1 interacting protein 1 Neighboring gene peroxiredoxin 3, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GCP5 and GCP6: two new members of the human gamma-tubulin complex. Murphy SM, et al. Mol Biol Cell, 2001 Nov. PMID 11694571, Free PMC Article
    2. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables gamma-tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    contributes_to microtubule minus-end binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule nucleation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of gamma-tubulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of gamma-tubulin ring complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    gamma-tubulin complex component 5
    Names
    tubulin, gamma complex associated protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107516.1 → NP_001100986.1  gamma-tubulin complex component 5

      See identical proteins and their annotated locations for NP_001100986.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474036
      UniProtKB/TrEMBL
      A0A8I6A219, A6KD27, D4A2A9
      Related
      ENSRNOP00000052843.4, ENSRNOT00000055989.6
      Conserved Domains (1) summary
      pfam04130
      Location:273 → 942
      Spc97_Spc98; Spc97 / Spc98 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      115772294..115807947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262318.1 → XP_063118388.1  gamma-tubulin complex component 5 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A219

    2. XM_063262319.1 → XP_063118389.1  gamma-tubulin complex component 5 isoform X2

    3. XM_063262321.1 → XP_063118391.1  gamma-tubulin complex component 5 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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