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    Saxo2 stabilizer of axonemal microtubules 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293061, updated on 9-Dec-2024

    Summary

    Official Symbol
    Saxo2provided by RGD
    Official Full Name
    stabilizer of axonemal microtubules 2provided by RGD
    Primary source
    RGD:1562653
    See related
    EnsemblRapid:ENSRNOG00000026296 AllianceGenome:RGD:1562653
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam154b; RGD1562653
    Summary
    Predicted to enable microtubule binding activity. Predicted to be active in microtubule cytoskeleton; nucleus; and sperm flagellum. Orthologous to human SAXO2 (stabilizer of axonemal microtubules 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 30.1), Testes (RPKM 17.6) and 8 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Saxo2 in Genome Data Viewer
    Location:
    1q31
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (146004694..146047662, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (136596445..136638444, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (144586260..144601358, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene SH3 domain containing GRB2 like 3, endophilin A3 Neighboring gene uncharacterized LOC134483750 Neighboring gene U6 snRNA-associated Sm-like protein LSm5 Neighboring gene ADAMTS-like 3 Neighboring gene small nucleolar RNA SNORA15 Neighboring gene elongation factor like GTPase 1 Neighboring gene mex-3 RNA binding family member B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in axonemal microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in sperm flagellum IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    stabilizer of axonemal microtubules 2
    Names
    family with sequence similarity 154, member B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106277.2NP_001099747.1  stabilizer of axonemal microtubules 2 isoform 2

      See identical proteins and their annotated locations for NP_001099747.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6GA21, A6JCK0, D3ZDP0
      Related
      ENSRNOP00000029587.4, ENSRNOT00000029244.7
    2. NM_001415797.1NP_001402726.1  stabilizer of axonemal microtubules 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A0G2JYT2, A0A8I6GA21
      Related
      ENSRNOP00000070779.1, ENSRNOT00000078144.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      146004694..146047662 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284801.1XP_063140871.1  stabilizer of axonemal microtubules 2 isoform X2

    2. XM_063284799.1XP_063140869.1  stabilizer of axonemal microtubules 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZN30, A0A8I6GA21
    3. XM_039105716.2XP_038961644.1  stabilizer of axonemal microtubules 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZN30, A0A8I6GA21
      Related
      ENSRNOP00000082886.2, ENSRNOT00000094717.2

    RNA

    1. XR_010064712.1 RNA Sequence