Saysd1 SAYSVFN motif domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Saysd1provided by RGD
Official Full Name: SAYSVFN motif domain containing 1provided by RGD
Primary source: RGD:1310877
See related: AllianceGenome:RGD:1310877
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1310877
Summary: Predicted to enable UFM1-modified protein reader activity. Predicted to be involved in protein quality control for misfolded or incompletely synthesized proteins and rescue of stalled ribosome. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in endoplasmic reticulum. Orthologous to human SAYSD1 (SAYSVFN motif domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 48.7), Kidney (RPKM 34.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 15p16

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (4273302..4278971)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (4224129..4229798)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (4657680..4663863)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables UFM1-modified protein reader activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in protein quality control for misfolded or incompletely synthesized proteins	ISO Inferred from Sequence Orthology more info
involved_in rescue of stalled ribosome	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: SAYSvFN domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.