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    CG13344 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36541, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13344provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033884
    Locus tag
    Dmel_CG13344
    See related
    AllianceGenome:FB:FBgn0033884
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:GreesD1; anon-EST:GressD1; Dmel\CG13344
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination; rescue of stalled ribosome; and ubiquitin-dependent protein catabolic process. Predicted to be active in nucleus. Orthologous to human RNF25 (ring finger protein 25). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13344 in Genome Data Viewer
    Location:
    50C6-50C6; 2-68 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13861997..13864156)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9749502..9751661)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tumbleweed Neighboring gene Ubiquitin-like activating enzyme 3 Neighboring gene short stop Neighboring gene DJ-1alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hybridization fingerprinting of high-density cDNA-library arrays with cDNA pools derived from whole tissues. Gress TM, et al. Mamm Genome, 1992. PMID 1450511
    2. TEMPLE: analysing population genetic variation at transcription factor binding sites. Litovchenko M, et al. Mol Ecol Resour, 2016 Nov. PMID 27106869
    3. The Extracellular and Cytoplasmic Domains of Syndecan Cooperate Postsynaptically to Promote Synapse Growth at the Drosophila Neuromuscular Junction. Nguyen MU, et al. PLoS One, 2016. PMID 26987116, Free PMC Article
    4. A screen for E3 ubiquitination ligases that genetically interact with the adaptor protein Cindr during Drosophila eye patterning. Ketosugbo KF, et al. PLoS One, 2017. PMID 29117266, Free PMC Article
    5. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in rescue of stalled ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13344-PA
    CG13344-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13861997..13864156
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137071.5 → NP_610915.2  uncharacterized protein Dmel_CG13344, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610915.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9I6, A8WHE3, D0IQC3
      Related
      FBpp0086712
      Conserved Domains (2) summary
      smart00591
      Location:7 → 115
      RWD; domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain
      pfam13639
      Location:120 → 186
      zf-RING_2; Ring finger domain

    2. NM_001032245.2 → NP_001027416.2  uncharacterized protein Dmel_CG13344, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027416.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9I6, A8WHE3, D0IQC3
      Conserved Domains (2) summary
      smart00591
      Location:7 → 115
      RWD; domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain
      pfam13639
      Location:120 → 186
      zf-RING_2; Ring finger domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z9I6 A1Z9I6
    Q7K199 Q7K199

    Gene LinkOut

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