fy fuzzy [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: fyprovided by FlyBase
Official Full Name: fuzzyprovided by FlyBase
Primary source: FLYBASE:FBgn0001084
Locus tag: Dmel_CG13396
See related: AllianceGenome:FB:FBgn0001084
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG13396; Dmel\CG13396; Fy; FY
Summary: Involved in establishment or maintenance of cell polarity. Is expressed in organism. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human FUZ (fuzzy planar cell polarity protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (8401476..8403280, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (8401476..8403280, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex.
Title: Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex.
the Planar Polarity Effector proteins inturned, fuzzy, and fritz interact physically and can modulate the accumulation of each other in wing cells.
Title: The proteins encoded by the Drosophila Planar Polarity Effector genes inturned, fuzzy and fritz interact physically and can re-pattern the accumulation of "upstream" Planar Cell Polarity proteins.
Functions in the downstream portion of the frizzled pathway.
Title: The function of the frizzled pathway in the Drosophila wing is dependent on inturned and fuzzy.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in establishment or maintenance of cell polarity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in non-motile cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info