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    CG8360 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34122, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8360provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032001
    Locus tag
    Dmel_CG8360
    See related
    AllianceGenome:FB:FBgn0032001
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LP03131; Dmel\CG8360
    Summary
    Predicted to enable cytidine deaminase activity and zinc ion binding activity. Predicted to be involved in cytidine deamination. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human CDA (cytidine deaminase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8360 in Genome Data Viewer
    Location:
    28F3-28F3; 2-30 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8212959..8214135)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8212959..8214135)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Single stranded-binding protein c31A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Sorting nexin 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy. Belozerov VE, et al. Mol Cell Biol, 2012 Sep. PMID 22801366, Free PMC Article
    2. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article
    3. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047, Free PMC Article
    4. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    5. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cytidine deaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cytidine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytidine deamination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytidine deamination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8360-PA
    CG8360-PC
    NP_001260232.1
    NP_609195.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8212959..8214135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273303.1 → NP_001260232.1  uncharacterized protein Dmel_CG8360, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260232.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLR3
      Conserved Domains (2) summary
      COG0295
      Location:24 → 153
      Cdd; Cytidine deaminase [Nucleotide transport and metabolism]
      cl00269
      Location:27 → 152
      cytidine_deaminase-like; Cytidine and deoxycytidylate deaminase zinc-binding region. The family contains cytidine deaminases, nucleoside deaminases, deoxycytidylate deaminases and riboflavin deaminases. Also included are the apoBec family of mRNA editing enzymes. All members ...

    2. NM_135351.3 → NP_609195.1  uncharacterized protein Dmel_CG8360, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609195.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLR3
      Related
      FBpp0088874
      Conserved Domains (2) summary
      COG0295
      Location:24 → 153
      Cdd; Cytidine deaminase [Nucleotide transport and metabolism]
      cl00269
      Location:27 → 152
      cytidine_deaminase-like; Cytidine and deoxycytidylate deaminase zinc-binding region. The family contains cytidine deaminases, nucleoside deaminases, deoxycytidylate deaminases and riboflavin deaminases. Also included are the apoBec family of mRNA editing enzymes. All members ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MS94 Q8MS94
    Q9VLR3 Q9VLR3

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