U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ugt301D1 UDP-glycosyltransferase family 301 member D1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35105, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Ugt301D1provided by FlyBase
    Official Full Name
    UDP-glycosyltransferase family 301 member D1provided by FlyBase
    Primary source
    FLYBASE:FBgn0032684
    Locus tag
    Dmel_CG10178
    See related
    AllianceGenome:FB:FBgn0032684
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10178; Dmel\CG10178; UGT301D1
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Ugt301D1 in Genome Data Viewer
    Location:
    36F6-36F6; 2-53 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18509560..18513512)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18509560..18513512)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene let-7 Complex Neighboring gene uncharacterized protein Neighboring gene grindelwald Neighboring gene kon-tiki Neighboring gene long non-coding RNA:CR44903 Neighboring gene uncharacterized protein Neighboring gene Phosphodiesterase 11

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila. Schnorrer F, et al. Dev Cell, 2007 May. PMID 17488626
    2. Endurance exercise and selective breeding for longevity extend Drosophila healthspan by overlapping mechanisms. Sujkowski A, et al. Aging (Albany NY), 2015 Aug. PMID 26298685, Free PMC Article
    3. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
    4. Functional and phylogenetic analyses of a putative Drosophila melanogaster UDP-glycosyltransferase gene. Luque T, et al. Insect Biochem Mol Biol, 2002 Dec. PMID 12429111
    5. Steroid Signaling Establishes a Female Metabolic State and Regulates SREBP to Control Oocyte Lipid Accumulation. Sieber MH, et al. Curr Biol, 2015 Apr 20. PMID 25802149, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glycosyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    UDP-glycosyltransferase family 301 member D1
    Names
    CG10178-PA
    CG10178-PB
    Ugt301D1-PA
    Ugt301D1-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18509560..18513512
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259150.2 → NP_001246079.1  UDP-glycosyltransferase family 301 member D1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246079.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V678, Q9VJ81
      Conserved Domains (2) summary
      PHA03392
      Location:12 → 483
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:37 → 483
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    2. NM_136038.3 → NP_609882.1  UDP-glycosyltransferase family 301 member D1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609882.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V678, Q9VJ81
      Related
      FBpp0080618
      Conserved Domains (2) summary
      PHA03392
      Location:12 → 483
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:37 → 483
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VJ81 Q9VJ81

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous