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    IFT46 Intraflagellar transport 46 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35114, updated on 9-Dec-2024

    Summary

    Official Symbol
    IFT46provided by FlyBase
    Official Full Name
    Intraflagellar transport 46provided by FlyBase
    Primary source
    FLYBASE:FBgn0032692
    Locus tag
    Dmel_CG15161
    See related
    AllianceGenome:FB:FBgn0032692
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15161; Dmel\CG15161
    Summary
    Involved in cilium assembly. Predicted to be located in cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in microtubule organizing center and motile cilium. Is expressed in several structures, including peripheral sensory precursor cell; sense organ; sensory cluster; sensory nervous system primordium; and sensory organ cell. Orthologous to human IFT46 (intraflagellar transport 46). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See IFT46 in Genome Data Viewer
    Location:
    36F7-36F7; 2-53 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18614339..18616106, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18614339..18616106, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ada2a-containing complex component 2 Neighboring gene Misexpression suppressor of ras 3 Neighboring gene Cytochrome P450 310a1 Neighboring gene pseudo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cilium assembly IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cilium assembly ISM
    Inferred from Sequence Model
    more info
    PubMed 
    involved_in intraciliary transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intraciliary transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cilium ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of intraciliary transport particle B IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of intraciliary transport particle B ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    intraflagellar transport 46
    Names
    CG15161-PA
    IFT46-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18614339..18616106 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136046.3NP_609890.2  intraflagellar transport 46 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609890.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYZ6, Q9VJ72
      Related
      FBpp0080628
      Conserved Domains (1) summary
      pfam12317
      Location:189409
      IFT46_B_C; Intraflagellar transport complex B protein 46 C terminal