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    CG6753 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41557, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6753provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038070
    Locus tag
    Dmel_CG6753
    See related
    AllianceGenome:FB:FBgn0038070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6753
    Summary
    Predicted to enable triacylglycerol lipase activity. Predicted to be involved in lipid metabolic process. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 8. Orthologous to human LIPK (lipase family member K); LIPM (lipase family member M); and LIPN (lipase family member N). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6753 in Genome Data Viewer
    Location:
    87C3-87C3; 3-52 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12640163..12642482, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8465885..8468204, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46351 Neighboring gene Dpp target gene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dietary Curcumin Intake and Its Effects on the Transcriptome and Metabolome of Drosophila melanogaster. Belcher S, et al. Int J Mol Sci, 2024 Jun 14. PMID 38928266, Free PMC Article
    2. Lipid-gene regulatory network reveals coregulations of triacylglycerol with phosphatidylinositol/lysophosphatidylinositol and with hexosyl-ceramide. Wang W, et al. Biochim Biophys Acta Mol Cell Biol Lipids, 2019 Feb. PMID 30521938
    3. Comparative and functional genomics of lipases in holometabolous insects. Horne I, et al. Insect Biochem Mol Biol, 2009 Aug. PMID 19540341
    4. Oviposition behaviour in Drosophila melanogaster: Genetic and behavioural decoupling between oviposition acceptance and preference for natural fruits. Fanara JJ, et al. J Evol Biol, 2023 Jan. PMID 36357966
    5. A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons. Richhariya S, et al. Sci Rep, 2017 Feb 14. PMID 28195208, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables triacylglycerol lipase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6753-PB
    NP_650219.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12640163..12642482 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141962.4 → NP_650219.2  uncharacterized protein Dmel_CG6753 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650219.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q32KF9, Q9VG46
      Conserved Domains (1) summary
      PLN02872
      Location:39 → 394
      PLN02872; triacylglycerol lipase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VG46 Q9VG46

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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