U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Acyp2 Acylphosphatase 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41910, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Acyp2provided by FlyBase
    Official Full Name
    Acylphosphatase 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0038363
    Locus tag
    Dmel_CG18505
    See related
    AllianceGenome:FB:FBgn0038363
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AcPDro2; CG18505; Dmel\CG18505
    Summary
    Enables acylphosphatase activity. Predicted to be located in cytoplasm. Is expressed in adult head. Orthologous to human ACYP1 (acylphosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Acyp2 in Genome Data Viewer
    Location:
    89A5-89A5; 3-58 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15792688..15793487)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11618410..11619209)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Uroporphyrinogen III synthase 2 Neighboring gene crossover suppressor on 3 of Gowen Neighboring gene non-specific lethal 1 Neighboring gene antisense RNA:CR45891 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Amyloid formation of a protein in the absence of initial unfolding and destabilization of the native state. Soldi G, et al. Biophys J, 2005 Dec. PMID 16169977, Free PMC Article
    2. Stabilization of a native protein mediated by ligand binding inhibits amyloid formation independently of the aggregation pathway. Soldi G, et al. J Med Chem, 2006 Oct 5. PMID 17004719
    3. Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility. De Simone A, et al. Proc Natl Acad Sci U S A, 2011 Dec 27. PMID 22160682, Free PMC Article
    4. Drosophila melanogaster acylphosphatase: a common ancestor for acylphosphatase isoenzymes of vertebrate species. Pieri A, et al. FEBS Lett, 1998 Aug 21. PMID 9744795
    5. Characterization of a novel Drosophila melanogaster acylphosphatase. Degl'Innocenti D, et al. FEBS Lett, 2003 Jan 30. PMID 12560098

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acylphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables acylphosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables acylphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    acylphosphatase 2
    Names
    Acyp2-PA
    Acyp2-PB
    CG18505-PA
    CG18505-PB
    acylphosphatase
    NP_001262612.1
    NP_650491.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15792688..15793487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275683.1 → NP_001262612.1  acylphosphatase 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262612.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q29QI6, Q9VF36
      UniProtKB/TrEMBL
      A0A0B4KG16
      Conserved Domains (1) summary
      pfam00708
      Location:13 → 100
      Acylphosphatase

    2. NM_142234.2 → NP_650491.1  acylphosphatase 2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650491.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q29QI6, Q9VF36
      UniProtKB/TrEMBL
      A0A0B4KG16
      Related
      FBpp0082628
      Conserved Domains (1) summary
      pfam00708
      Location:13 → 100
      Acylphosphatase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KG16 A0A0B4KG16
    Q9VF36.1 Q9VF36

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools