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    yellow-h yellow-h [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43779, updated on 9-Dec-2024

    Summary

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    Official Symbol
    yellow-hprovided by FlyBase
    Official Full Name
    yellow-hprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039896
    Locus tag
    Dmel_CG1629
    See related
    AllianceGenome:FB:FBgn0039896
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1629; Dmel\CG1629; DPT; yell-h
    Summary
    Enables dopaminechrome tautomerase activity. Involved in melanin biosynthetic process from tyrosine. Predicted to be active in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See yellow-h in Genome Data Viewer
    Location:
    102B1-102B1; 4-0 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (227922..230428)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (248548..251054)

    Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene Crk oncogene Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene antisense RNA:CR46065 Neighboring gene uncharacterized protein Neighboring gene defective proboscis extension response 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila yellow-h encodes dopaminechrome tautomerase: A new enzyme in the eumelanin biosynthetic pathway. Barek H, et al. Pigment Cell Melanoma Res, 2022 Jan. PMID 34388859
    2. The Family of Yellow-Related Drosophila melanogaster Proteins. Drapeau MD. Biochem Biophys Res Commun, 2001 Mar 2. PMID 11237700
    3. Evolution of the insect yellow gene family. Ferguson LC, et al. Mol Biol Evol, 2011 Jan. PMID 20656794
    4. Gene transposition as a cause of hybrid sterility in Drosophila. Masly JP, et al. Science, 2006 Sep 8. PMID 16960009
    5. Evolutionary changes in cis and trans gene regulation. Wittkopp PJ, et al. Nature, 2004 Jul 1. PMID 15229602

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Drosophila yellow-h encodes dopaminechrome tautomerase: A new enzyme in the eumelanin biosynthetic pathway.
      Title: Drosophila yellow-h encodes dopaminechrome tautomerase: A new enzyme in the eumelanin biosynthetic pathway.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dopaminechrome tautomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in melanin biosynthetic process from tyrosine IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    yellow-h
    Names
    CG1629-PA
    dopaminechrome tautomerase
    yellow-h-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.4 Reference assembly

      Range
      227922..230428
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143655.4 → NP_651912.3  yellow-h [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651912.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SZ51, Q9V4C0
      Related
      FBpp0088184
      Conserved Domains (1) summary
      pfam03022
      Location:148 → 440
      MRJP; Major royal jelly protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V4C0.2 Q9V4C0

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