CatB Catalase B [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CatBprovided by FlyBase
Official Full Name: Catalase Bprovided by FlyBase
Primary source: FLYBASE:FBgn0032061
Locus tag: Dmel_CG9314
See related: AllianceGenome:FB:FBgn0032061
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0140519.249; CG9314; CT26521; Dmel\CG9314
Summary: Predicted to enable catalase activity and heme binding activity. Predicted to be involved in hydrogen peroxide catabolic process and response to hydrogen peroxide. Predicted to be active in mitochondrion and peroxisome. Is expressed in adult head; spermatozoon; wing hinge primordium; and wing pouch. Human ortholog(s) of this gene implicated in several diseases, including acatalasia; eye disease (multiple); lung disease (multiple); osteonecrosis; and pseudoxanthoma elasticum. Orthologous to human CAT (catalase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (8705572..8707527)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (8705572..8707527)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables catalase activity	IBA Inferred from Biological aspect of Ancestor more info
enables catalase activity	IEA Inferred from Electronic Annotation more info
enables catalase activity	ISS Inferred from Sequence or Structural Similarity more info
enables heme binding	IBA Inferred from Biological aspect of Ancestor more info
enables heme binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in hydrogen peroxide catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to hydrogen peroxide	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info
involved_in response to oxidative stress	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
is_active_in peroxisome	IBA Inferred from Biological aspect of Ancestor more info

NP_001260268.1

NP_609248.1

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The following sections contain reference sequences that belong to a specific genome build. Explain