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    CG5790 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35095, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5790provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032677
    Locus tag
    Dmel_CG5790
    See related
    AllianceGenome:FB:FBgn0032677
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5790
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic DNA damage checkpoint signaling. Part of Dbf4-dependent protein kinase complex. Orthologous to human CDC7 (cell division cycle 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5790 in Genome Data Viewer
    Location:
    36F2-36F2; 2-53 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18294840..18297347)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18294840..18297347)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43358 Neighboring gene Seminal fluid protein 36F Neighboring gene long non-coding RNA:CR43353 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of a Drosophila ortholog of the Cdc7 kinase: a role for Cdc7 in endoreplication independent of Chiffon. Stephenson R, et al. J Biol Chem, 2015 Jan 16. PMID 25451925, Free PMC Article
    2. Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila. Reid DW, et al. Front Cell Infect Microbiol, 2012. PMID 22919616, Free PMC Article
    3. Drosophila muscleblind is involved in troponin T alternative splicing and apoptosis. Vicente-Crespo M, et al. PLoS One, 2008 Feb 20. PMID 18286170, Free PMC Article
    4. Sex-specific role of Drosophila melanogaster HP1 in regulating chromatin structure and gene transcription. Liu LP, et al. Nat Genet, 2005 Dec. PMID 16258543
    5. Numerous Serine/Threonine Kinases Affect Blood Cell Homeostasis in Drosophila melanogaster. Deichsel S, et al. Cells, 2024 Mar 26. PMID 38607015, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic DNA damage checkpoint signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Dbf4-dependent protein kinase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CDC 7-related
    CG5790-PA
    CG5790-PB
    NP_001286037.1
    NP_609876.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18294840..18297347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299108.1 → NP_001286037.1  uncharacterized protein Dmel_CG5790, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286037.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJ90
      Conserved Domains (3) summary
      smart00220
      Location:145 → 597
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14019
      Location:143 → 597
      STKc_Cdc7; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase
      cl21453
      Location:427 → 597
      PKc_like; Protein Kinases, catalytic domain

    2. NM_136032.4 → NP_609876.2  uncharacterized protein Dmel_CG5790, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609876.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJ90
      Related
      FBpp0080603
      Conserved Domains (3) summary
      smart00220
      Location:145 → 597
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14019
      Location:143 → 597
      STKc_Cdc7; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase
      cl21453
      Location:427 → 597
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T0Q5 Q8T0Q5
    Q9VJ90 Q9VJ90

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