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    CG3793 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34928, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3793provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028507
    Locus tag
    Dmel_CG3793
    See related
    AllianceGenome:FB:FBgn0028507
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS09217.4; Dmel\CG3793
    Summary
    Predicted to enable protein C-terminal leucine carboxyl O-methyltransferase activity. Predicted to be involved in regulation of mitotic cell cycle spindle assembly checkpoint. Predicted to be active in cytosol. Is expressed in adult head and organism. Orthologous to human LCMT1 (leucine carboxyl methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3793 in Genome Data Viewer
    Location:
    35D4-35D4; 2-51 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15764220..15766267)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15764220..15766267)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Mtr4 helicase Neighboring gene Gliotactin Neighboring gene weckle Neighboring gene Ku80 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide P-element screen for Drosophila synaptogenesis mutants. Liebl FL, et al. J Neurobiol, 2006 Mar. PMID 16408305, Free PMC Article
    2. A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth. Laviolette MJ, et al. Genetics, 2005 Jun. PMID 15834148, Free PMC Article
    3. The genetic basis of natural variation in mushroom body size in Drosophila melanogaster. Zwarts L, et al. Nat Commun, 2015 Dec 11. PMID 26656654, Free PMC Article
    4. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Ashburner M, et al. Genetics, 1999 Sep. PMID 10471707, Free PMC Article
    5. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein C-terminal leucine carboxyl O-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mitotic cell cycle spindle assembly checkpoint IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3793-PA
    CG3793-PB
    NP_001246038.1
    NP_609766.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15764220..15766267
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259109.2 → NP_001246038.1  uncharacterized protein Dmel_CG3793, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246038.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NF32
      Conserved Domains (1) summary
      pfam04072
      Location:22 → 211
      LCM; Leucine carboxyl methyltransferase

    2. NM_135922.3 → NP_609766.1  uncharacterized protein Dmel_CG3793, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609766.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V3K7
      Related
      FBpp0080320
      Conserved Domains (1) summary
      pfam04072
      Location:22 → 211
      LCM; Leucine carboxyl methyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NF32 M9NF32
    Q9V3K7 Q9V3K7

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