Vps51 Vacuolar protein sorting 51 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Vps51provided by FlyBase
Official Full Name: Vacuolar protein sorting 51provided by FlyBase
Primary source: FLYBASE:FBgn0034380
Locus tag: Dmel_CG15087
See related: AllianceGenome:FB:FBgn0034380
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG15087; Dmel\CG15087
Summary: Predicted to be involved in several processes, including Golgi organization; endosomal transport; and lysosomal transport. Predicted to be part of EARP complex and GARP complex. Predicted to be active in membrane. Is expressed in adult head; organism; and spermatozoon. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 13. Orthologous to human VPS51 (VPS51 subunit of GARP complex). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (18708152..18710865, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (14595657..14598370, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in Golgi organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in Golgi vesicle transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in endocytic recycling	IBA Inferred from Biological aspect of Ancestor more info
involved_in endocytic recycling	ISS Inferred from Sequence or Structural Similarity more info
involved_in lysosomal transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in retrograde transport, endosome to Golgi	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of EARP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of GARP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of GARP complex	ISS Inferred from Sequence or Structural Similarity more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain