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    CG7536 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32786, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7536provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030890
    Locus tag
    Dmel_CG7536
    See related
    AllianceGenome:FB:FBgn0030890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7536
    Summary
    Predicted to enable inositol hexakisphosphate binding activity and phosphate transmembrane transporter activity. Predicted to be involved in cellular response to phosphate starvation and phosphate ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; embryonic large intestine; embryonic/larval midgut primordium; foregut primordium; and gut section. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human XPR1 (xenotropic and polytropic retrovirus receptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7536 in Genome Data Viewer
    Location:
    16F6-16F6; 1-59 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18078491..18088532, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17972524..17982565, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Shaker Neighboring gene uncharacterized protein Neighboring gene Dynein heavy chain at 16F Neighboring gene transcriptional Adaptor 3 Neighboring gene Swt1 RNA endoribonuclease Neighboring gene scully

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods. Denecke SM, et al. Genome Biol Evol, 2020 Aug 1. PMID 32681801, Free PMC Article
    2. X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. Legube G, et al. Genes Dev, 2006 Apr 1. PMID 16547175, Free PMC Article
    3. Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster. Manta AK, et al. Fly (Austin), 2017 Apr 3. PMID 27960592, Free PMC Article
    4. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204
    5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables inositol hexakisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to phosphate starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphate ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7536-PA
    CG7536-PB
    CG7536-PC
    CG7536-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      18078491..18088532 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298469.1 → NP_001285398.1  uncharacterized protein Dmel_CG7536, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285398.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960X7, Q9VWZ2
      Conserved Domains (3) summary
      cd14477
      Location:2 → 156
      SPX_XPR1_like; SPX domain of the xenotropic and polytropic retrovirus receptor 1 (XPR1) and related proteins
      pfam03105
      Location:3 → 158
      SPX; SPX domain
      pfam03124
      Location:258 → 597
      EXS; EXS family

    2. NM_167599.2 → NP_728131.1  uncharacterized protein Dmel_CG7536, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728131.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960X7, Q9VWZ2
      Related
      FBpp0074304
      Conserved Domains (3) summary
      cd14477
      Location:2 → 156
      SPX_XPR1_like; SPX domain of the xenotropic and polytropic retrovirus receptor 1 (XPR1) and related proteins
      pfam03105
      Location:3 → 158
      SPX; SPX domain
      pfam03124
      Location:258 → 597
      EXS; EXS family

    3. NM_001298470.1 → NP_001285399.1  uncharacterized protein Dmel_CG7536, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285399.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960X7, Q9VWZ2
      Conserved Domains (3) summary
      cd14477
      Location:2 → 156
      SPX_XPR1_like; SPX domain of the xenotropic and polytropic retrovirus receptor 1 (XPR1) and related proteins
      pfam03105
      Location:3 → 158
      SPX; SPX domain
      pfam03124
      Location:258 → 597
      EXS; EXS family

    4. NM_133037.3 → NP_573265.1  uncharacterized protein Dmel_CG7536, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573265.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960X7, Q9VWZ2
      Related
      FBpp0074305
      Conserved Domains (3) summary
      cd14477
      Location:2 → 156
      SPX_XPR1_like; SPX domain of the xenotropic and polytropic retrovirus receptor 1 (XPR1) and related proteins
      pfam03105
      Location:3 → 158
      SPX; SPX domain
      pfam03124
      Location:258 → 597
      EXS; EXS family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VWZ2 Q9VWZ2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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