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    Igkv4-70 immunoglobulin kappa chain variable 4-70 [ Mus musculus (house mouse) ]

    Gene ID: 385120, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Igkv4-70provided by MGI
    Official Full Name
    immunoglobulin kappa chain variable 4-70provided by MGI
    Primary source
    MGI:MGI:2686348
    See related
    IMGT/GENE-DB:IGKV4-70; AllianceGenome:MGI:2686348
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    kn4; BH151; Gm1502
    Summary
    Predicted to be involved in immune response. Predicted to be part of immunoglobulin complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Igkv4-70 in Genome Data Viewer
    Location:
    6 C1; 6 31.44 cM
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (69244872..69245396, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (69267888..69268412, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa chain complex Neighboring gene immunoglobulin kappa chain variable 13-71-1 Neighboring gene STARR-seq mESC enhancer starr_16209 Neighboring gene immunoglobulin kappa chain variable 4-71 Neighboring gene immunoglobulin kappa variable 4-69 Neighboring gene immunoglobulin kappa variable 4-68

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural evidence for recognition of a single epitope by two distinct antibodies. Fleury D, et al. Proteins, 2000 Sep 1. PMID 10899782
    2. Crystallization and preliminary X-ray diffraction studies of complexes between an influenza hemagglutinin and Fab fragments of two different monoclonal antibodies. Gigant B, et al. Proteins, 1995 Sep. PMID 8539243
    3. Human myeloperoxidase in innate and acquired immunity. Arnhold J, et al. Arch Biochem Biophys, 2010 Aug 1. PMID 20399194
    4. Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome. Schäble KF, et al. Eur J Immunol, 1999 Jul. PMID 10427970
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • anti-MOG Z12 variable light chain
    • anti-MOG kappa
    • immunoglobulin light chain variable region

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of immunoglobulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_005612.1 

      Range
      1712908..1713432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      69244872..69245396 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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