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    Mir142hg Mir142 host gene (non-protein coding) [ Mus musculus (house mouse) ]

    Gene ID: 78591, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mir142hgprovided by MGI
    Official Full Name
    Mir142 host gene (non-protein coding)provided by MGI
    Primary source
    MGI:MGI:1925841
    See related
    AllianceGenome:MGI:1925841
    Gene type
    protein coding
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A430104N18Rik
    Summary
    Acts upstream of or within dendritic cell homeostasis. Is expressed in lung. [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    11 52.21 cM

    Bibliography

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    Related articles in PubMed

    1. MiR-142-3p regulates synaptopathy-driven disease progression in multiple sclerosis. De Vito F, et al. Neuropathol Appl Neurobiol, 2022 Feb. PMID 34490928, Free PMC Article
    2. Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis. Mildner A, et al. Blood, 2013 Feb 7. PMID 23212522
    3. MicroRNA-142-3p facilitates inflammatory response by targeting ZEB2 and activating NF-κB signaling in gouty arthritis. Lu Y, et al. Cell Cycle, 2022 Apr. PMID 35239453, Free PMC Article
    4. RNA viruses can hijack vertebrate microRNAs to suppress innate immunity. Trobaugh DW, et al. Nature, 2014 Feb 13. PMID 24352241, Free PMC Article
    5. miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis. Chapnik E, et al. Elife, 2014 May 23. PMID 24859754, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MicroRNA-142-3p facilitates inflammatory response by targeting ZEB2 and activating NF-kappaB signaling in gouty arthritis.
      Title: MicroRNA-142-3p facilitates inflammatory response by targeting ZEB2 and activating NF-κB signaling in gouty arthritis.
    2. results suggest that the glucocorticoid-miR-142-Ep300-beta-catenin signaling axis controls pneumocyte maturation
      Title: A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development.
    3. Significantly lower miR-142-3p levels were observed in plasma MP of Cd39 null mice after partial hepatectomy
      Title: Mononuclear-cell-derived microparticles attenuate endothelial inflammation by transfer of miR-142-3p in a CD39 dependent manner.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

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    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within dendritic cell homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein LOC78591
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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