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    FMP42 Fmp42p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855261, updated on 9-Dec-2024

    Summary

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    Official Symbol
    FMP42
    Official Full Name
    Fmp42p
    Primary source
    SGD:S000004834
    Locus tag
    YMR221C
    See related
    AllianceGenome:SGD:S000004834; FungiDB:YMR221C; VEuPathDB:YMR221C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in fungal-type vacuole membrane and mitochondrion. Orthologous to human SLC43A1 (solute carrier family 43 member 1); SLC43A2 (solute carrier family 43 member 2); and SLC43A3 (solute carrier family 43 member 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See FMP42 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (713931..715445, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Esc1p Neighboring gene phosphomevalonate kinase Neighboring gene putative serine hydrolase Neighboring gene ubiquitin-specific protease UBP8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The yeast vacuolar membrane proteome. Wiederhold E, et al. Mol Cell Proteomics, 2009 Feb. PMID 19001347
    2. Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Fromont-Racine M, et al. Yeast, 2000 Jun 30. PMID 10900456, Free PMC Article
    3. Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7. Logan MR, et al. BMC Genomics, 2008 Jul 15. PMID 18627629, Free PMC Article
    4. A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. McCormick MA, et al. Cell Metab, 2015 Nov 3. PMID 26456335, Free PMC Article
    5. Multiplex assay for condition-dependent changes in protein-protein interactions. Schlecht U, et al. Proc Natl Acad Sci U S A, 2012 Jun 5. PMID 22615397, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in fungal-type vacuole HDA PubMed 
    located_in fungal-type vacuole membrane HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fmp42p
    NP_013948.1
    • hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; physical interaction with Atg27p suggests a possible role in autophagy; targeted to vacuole via AP-3 pathway

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      713931..715445 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182728.1 → NP_013948.1  TPA: Fmp42p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013948.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W046, Q04991
      UniProtKB/TrEMBL
      B3LMA9, C7GRD0, C8ZF85, G2WKS8, N1P5V0
      Conserved Domains (1) summary
      cl28910
      Location:11 → 205
      MFS; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04991.1

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