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    ISF1 Isf1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855105, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ISF1
    Official Full Name
    Isf1p
    Primary source
    SGD:S000004686
    Locus tag
    YMR081C
    See related
    AllianceGenome:SGD:S000004686; FungiDB:YMR081C; VEuPathDB:YMR081C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MBR3
    Summary
    Involved in aerobic respiration. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ISF1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (430079..431095, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol/phosphatidylcholine transfer protein SEC14 Neighboring gene ATP-dependent RNA helicase NAM7 Neighboring gene uncharacterized protein Neighboring gene alcohol dehydrogenase ADH3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The transcription of NAM7/UPF1 is enhanced in the absence of Cyp1p/Hap1p concomitant with the appearance of an ISF1-NAM7 cotranscript in Saccharomyces cerevisiae. Altamura N, et al. FEBS Lett, 1997 Jun 2. PMID 9199511
    2. Two adjacent nuclear genes, ISF1 and NAM7/UPF1, cooperatively participate in mitochondrial functions in Saccharomyces cerevisiae. Altamura N, et al. Mol Gen Genet, 1994 Jan. PMID 7506349
    3. SIT4 regulation of Mig1p-mediated catabolite repression in Saccharomyces cerevisiae. Jin C, et al. FEBS Lett, 2007 Dec 11. PMID 18022394, Free PMC Article
    4. MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants. Daignan-Fornier B, et al. Mol Gen Genet, 1994 Jun 3. PMID 8208248
    5. Analysis of the Physiological Activities of Scd6 through Its Interaction with Hmt1. Lien PT, et al. PLoS One, 2016. PMID 27776129, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in aerobic respiration IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Isf1p
    NP_013798.1
    • Serine-rich, hydrophilic protein; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant; ISF1 has a paralog, MBR1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      430079..431095 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182580.1 → NP_013798.1  TPA: Isf1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013798.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3LLX4, B5VPK7, C7GL43, C8ZET4, D6VZQ5, P32488
      UniProtKB/TrEMBL
      N1NYQ8
      Conserved Domains (1) summary
      pfam17058
      Location:6 → 178
      MBR1; Mitochondrial biogenesis regulation protein 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32488.1

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