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    AIM26 Aim26p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853829, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AIM26
    Official Full Name
    Aim26p
    Primary source
    SGD:S000001520
    Locus tag
    YKL037W
    See related
    AllianceGenome:SGD:S000001520; FungiDB:YKL037W; VEuPathDB:YKL037W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in autophagy of mitochondrion and macroautophagy. Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See AIM26 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (369365..369721)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Rgt1p Neighboring gene UTP glucose-1-phosphate uridylyltransferase Neighboring gene ubiquitin-protein ligase TUL1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The sequence of a 12 kb fragment on the left arm of yeast chromosome XI reveals five new open reading frames, including a zinc finger protein and a homolog of the UDP-glucose pyrophosphorylase from potato. Purnelle B, et al. Yeast, 1992 Nov. PMID 1481573
    2. Yeast β-1,6-glucan is a primary target for the Saccharomyces cerevisiae K2 toxin. Lukša J, et al. Eukaryot Cell, 2015 Apr. PMID 25710965, Free PMC Article
    3. Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae. Tan SX, et al. Mol Biol Cell, 2009 Mar. PMID 19129474, Free PMC Article
    4. A Chemogenomic Screening Platform Used to Identify Chemotypes Perturbing HSP90 Pathways. Thomas FM, et al. SLAS Discov, 2017 Jul. PMID 28346089, Free PMC Article
    5. Mass-murdering: deletion of twenty-three ORFs from Saccharomyces cerevisiae chromosome XI reveals five genes essential for growth and three genes conferring detectable mutant phenotype. Wysocki R, et al. Gene, 1999 Mar 18. PMID 10095102

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in autophagy of mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in macroautophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Aim26p
    NP_012887.1
    • hypothetical protein; null mutant is viable and displays elevated frequency of mitochondrial genome loss; null mutation confers sensitivity to tunicamycin and DTT

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      369365..369721
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179603.1 → NP_012887.1  TPA: Aim26p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012887.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXP9, P32858
      UniProtKB/TrEMBL
      B3LR50, C7GP36
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32858.1

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