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    PAL1 Pal1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851949, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PAL1
    Official Full Name
    Pal1p
    Primary source
    SGD:S000002756
    Locus tag
    YDR348C
    See related
    AllianceGenome:SGD:S000002756; FungiDB:YDR348C; VEuPathDB:YDR348C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in endocytosis. Located in actin cortical patch. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PAL1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1170326..1171825, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Svf1p Neighboring gene mitochondrial 37S ribosomal protein MRP1 Neighboring gene putative aspartic endopeptidase Neighboring gene tRNA-Met

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in actin cortical patch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud neck HDA PubMed 
    located_in cellular bud tip HDA PubMed 
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mating projection tip HDA PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pal1p
    NP_010635.1
    • hypothetical protein thought to be involved in endocytosis; physically interacts with Ede1p and is found at endocytic sites at cell periphery during early stages of endocytosis; green fluorescent protein (GFP)-fusion protein localizes to bud neck; potential Cdc28p substrate; similar to S. pombe Pal1 protein; relocalizes from bud neck to cytoplasm upon DNA replication stress; PAL1 has a paralog, YHR097C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1170326..1171825 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180656.1 → NP_010635.1  TPA: Pal1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010635.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSX8, Q05518, Q66RD5
      UniProtKB/TrEMBL
      A6ZYU8, B3LFV2, C8Z5Q9, N1PAI3
      Conserved Domains (1) summary
      pfam08316
      Location:236 → 369
      Pal1; Pal1 cell morphology protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05518.1

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