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    MRX9 Mrx9p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851535, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRX9
    Official Full Name
    Mrx9p
    Primary source
    SGD:S000002185
    Locus tag
    YDL027C
    See related
    AllianceGenome:SGD:S000002185; FungiDB:YDL027C; VEuPathDB:YDL027C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRX9 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (403695..404957, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene actin-related protein 2 Neighboring gene serine/threonine/tyrosine protein kinase MPS1 Neighboring gene putative serine/threonine protein kinase RTK1 Neighboring gene putative acid phosphatase DIA3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Increased mitochondrial respiration promotes survival from endoplasmic reticulum stress. Knupp J, et al. Cell Death Differ, 2019 Mar. PMID 29795335, Free PMC Article
    2. Overexpression of MRX9 impairs processing of RNAs encoding mitochondrial oxidative phosphorylation factors COB and COX1 in yeast. Chagas JAC, et al. J Biol Chem, 2022 Aug. PMID 35779633, Free PMC Article
    3. Organization of Mitochondrial Gene Expression in Two Distinct Ribosome-Containing Assemblies. Kehrein K, et al. Cell Rep, 2015 Feb 17. PMID 25683707
    4. Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics. Díaz-Mejía JJ, et al. Mol Syst Biol, 2018 May 28. PMID 29807908, Free PMC Article
    5. A meiotic XPF-ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation. De Muyt A, et al. Genes Dev, 2018 Feb 1. PMID 29440262, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of MRX9 impairs processing of RNAs encoding mitochondrial oxidative phosphorylation factors COB and COX1 in yeast.
      Title: Overexpression of MRX9 impairs processing of RNAs encoding mitochondrial oxidative phosphorylation factors COB and COX1 in yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mrx9p
    NP_010257.1
    • Mitochondrial inner membrane protein; high copy suppressor of ER stress-mediated cell death; overexpression increases O2 consumption, impairs processing of COB and COX1 RNAs encoding mitochondrial oxidative phosphorylation factors, and impacts the transition from fermentative to respiratory metabolism

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      403695..404957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180086.1 → NP_010257.1  TPA: Mrx9p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010257.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRW5, Q05321, Q05435, Q07349, Q7LHC7
      UniProtKB/TrEMBL
      A6ZXU4, B3LGT0, B5VFN9, N1P5X1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07349.1

    Gene LinkOut

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