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    Cep192 centrosomal protein 192 [ Mus musculus (house mouse) ]

    Gene ID: 70799, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cep192provided by MGI
    Official Full Name
    centrosomal protein 192provided by MGI
    Primary source
    MGI:MGI:1918049
    See related
    Ensembl:ENSMUSG00000024542 AllianceGenome:MGI:1918049
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4631422C13Rik; D430014P18Rik
    Summary
    Predicted to enable phosphatase binding activity and protein kinase binding activity. Acts upstream of or within response to bacterium. Located in cytoplasm and pericentriolar material. Is expressed in cerebral cortex ventricular layer and meninges. Orthologous to human CEP192 (centrosomal protein 192). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 7.7), limb E14.5 (RPKM 5.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cep192 in Genome Data Viewer
    Location:
    18 E1- E2; 18 40.11 cM
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (67933124..68018241)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (67800054..67885170)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930549G23 gene Neighboring gene STARR-positive B cell enhancer ABC_E11001 Neighboring gene STARR-positive B cell enhancer ABC_E1518 Neighboring gene predicted gene, 26910 Neighboring gene STARR-positive B cell enhancer ABC_E11662 Neighboring gene SEH1-like (S. cerevisiae Neighboring gene STARR-seq mESC enhancer starr_44916 Neighboring gene STARR-seq mESC enhancer starr_44917 Neighboring gene STARR-seq mESC enhancer starr_44919 Neighboring gene tubulin, alpha 1B pseudogene Neighboring gene STARR-seq mESC enhancer starr_44922 Neighboring gene low density lipoprotein receptor class A domain containing 4 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:68126707-68126976 Neighboring gene predicted gene, 52336

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in pericentriolar material IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in pericentriolar material IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in procentriole ISO
    Inferred from Sequence Orthology
    more info
     
    part_of procentriole replication complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    centrosomal protein of 192 kDa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027556.1NP_081832.1  centrosomal protein of 192 kDa

      Status: VALIDATED

      Source sequence(s)
      AC127236, AK052420, AK158414, BC064462, BE982606, CD538408, CK391255, CK639048, CO045915
      Consensus CDS
      CCDS50313.1
      UniProtKB/TrEMBL
      E9Q4Y4
      Related
      ENSMUSP00000025425.6, ENSMUST00000025425.7
      Conserved Domains (1) summary
      cl13764
      Location:16361703
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      67933124..68018241
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526241.3XP_006526304.1  centrosomal protein of 192 kDa isoform X1

      See identical proteins and their annotated locations for XP_006526304.1

      Conserved Domains (2) summary
      pfam08626
      Location:16511772
      TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
      cl13764
      Location:16361703
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    2. XM_011247001.4XP_011245303.1  centrosomal protein of 192 kDa isoform X5

      Conserved Domains (2) summary
      pfam08626
      Location:16511772
      TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
      cl13764
      Location:16361703
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    3. XM_006526243.4XP_006526306.1  centrosomal protein of 192 kDa isoform X2

      Conserved Domains (2) summary
      pfam08626
      Location:16081729
      TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
      cl13764
      Location:15931660
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    4. XM_006526242.3XP_006526305.1  centrosomal protein of 192 kDa isoform X1

      See identical proteins and their annotated locations for XP_006526305.1

      Conserved Domains (2) summary
      pfam08626
      Location:16511772
      TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
      cl13764
      Location:16361703
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    5. XM_036161275.1XP_036017168.1  centrosomal protein of 192 kDa isoform X3

      Conserved Domains (1) summary
      cl13764
      Location:14061473
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    6. XM_011247000.4XP_011245302.1  centrosomal protein of 192 kDa isoform X4

      Conserved Domains (2) summary
      pfam08626
      Location:10191140
      TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
      cl13764
      Location:10041071
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin