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    EMA35 Ema35p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850464, updated on 9-Dec-2024

    Summary

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    Official Symbol
    EMA35
    Official Full Name
    Ema35p
    Primary source
    SGD:S000000697
    Locus tag
    YCR100C
    See related
    AllianceGenome:SGD:S000000697; FungiDB:YCR100C; VEuPathDB:YCR100C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be located in membrane. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm. Orthologous to human SORT1 (sortilin 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See EMA35 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (301271..302221, complement)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene tRNA-Thr Neighboring gene Git1p Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An ER surface retrieval pathway safeguards the import of mitochondrial membrane proteins in yeast. Hansen KG, et al. Science, 2018 Sep 14. PMID 30213914
    2. The complete DNA sequence of yeast chromosome III. Oliver SG, et al. Nature, 1992 May 7. PMID 1574125
    3. Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins. Tonikian R, et al. PLoS Biol, 2009 Oct. PMID 19841731, Free PMC Article
    4. Association of yeast Upf1p with direct substrates of the NMD pathway. Johansson MJ, et al. Proc Natl Acad Sci U S A, 2007 Dec 26. PMID 18087042, Free PMC Article
    5. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ema35p
    NP_010024.1
    • Protein involved in protein sorting; involved in targeting mitochondrial membrane proteins to mitochondrial translocation system; mutation causes respiration defects

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      301271..302221 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178807.1 → NP_010024.1  TPA: Ema35p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010024.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRA1, P25606
      UniProtKB/TrEMBL
      B3LUF3, B5VF30
      Conserved Domains (1) summary
      smart00602
      Location:1 → 316
      VPS10; VPS10 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25606.1

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