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    PSP1 Psp1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852116, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PSP1
    Official Full Name
    Psp1p
    Primary source
    SGD:S000002913
    Locus tag
    YDR505C
    See related
    AllianceGenome:SGD:S000002913; FungiDB:YDR505C; VEuPathDB:YDR505C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    GIN5
    Summary
    Enables mRNA binding activity. Located in P-body. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PSP1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1456695..1459220, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene phosphatidate phosphatase LPP1 Neighboring gene Spg3p Neighboring gene putative oxidoreductase Neighboring gene tRNA-Leu

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Screening and identification of yeast sequences that cause growth inhibition when overexpressed. Akada R, et al. Mol Gen Genet, 1997 Apr 16. PMID 9150260
    2. Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiae. Formosa T, et al. Mol Gen Genet, 1998 Feb. PMID 9529527
    3. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol-binding proteins in Saccharomyces cerevisiae. Chauhan N, et al. Yeast, 2020 Jan. PMID 31758572
    4. Dosage rescue by UBC4 restores cell wall integrity in Saccharomyces cerevisiae lacking the myosin type II gene MYO1. Díaz-Blanco NL, et al. Yeast, 2007 Apr. PMID 17397110, Free PMC Article
    5. Distinct roles of Rho1, Cdc42, and Cyk3 in septum formation and abscission during yeast cytokinesis. Onishi M, et al. J Cell Biol, 2013 Jul 22. PMID 23878277, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in P-body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Psp1p
    NP_010793.2
    • Asn and gln rich hypothetical protein; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition; capable of forming the prion [PSP1+]; PSP1 has a paralog, YLR177W, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1456695..1459220 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180813.2 → NP_010793.2  TPA: Psp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010793.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTC7, P50896
      UniProtKB/TrEMBL
      B3LFG3, G2WBN3, N1PAL5
      Conserved Domains (1) summary
      COG1774
      Location:581 → 838
      YaaT; Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development) [Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P50896.2

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