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    RPS8B ribosomal 40S subunit protein S8B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856839, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPS8B
    Official Full Name
    ribosomal 40S subunit protein S8B
    Primary source
    SGD:S000000904
    Locus tag
    YER102W
    See related
    AllianceGenome:SGD:S000000904; FungiDB:YER102W; VEuPathDB:YER102W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    A structural constituent of ribosome. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Orthologous to human RPS8 (ribosomal protein S8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPS8B in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (363100..363702)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene E2 ubiquitin-conjugating protein UBC6 Neighboring gene Ast2p Neighboring gene Hsp70 family chaperone SSA4 Neighboring gene Rtt105p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The DEAH-box helicase Dhr1 dissociates U3 from the pre-rRNA to promote formation of the central pseudoknot. Sardana R, et al. PLoS Biol, 2015 Feb. PMID 25710520, Free PMC Article
    2. Histone variant H2A.Z functions in sister chromatid cohesion in Saccharomyces cerevisiae. Sharma U, et al. Mol Cell Biol, 2013 Sep. PMID 23816883, Free PMC Article
    3. Dual binding mode of the nascent polypeptide-associated complex reveals a novel universal adapter site on the ribosome. Pech M, et al. J Biol Chem, 2010 Jun 18. PMID 20410297, Free PMC Article
    4. Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Schäfer T, et al. Nature, 2006 Jun 1. PMID 16738661
    5. In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation. Cheng J, et al. Nucleic Acids Res, 2022 Nov 11. PMID 36263816, Free PMC Article

    See all (62) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S8B
    NP_011028.1
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S8, no bacterial homolog; RPS8B has a paralog, RPS8A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      363100..363702
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178993.1 → NP_011028.1  TPA: ribosomal 40S subunit protein S8B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011028.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2TBM0, A2TBP0, D3DM09, P05754, P0CX39, P0CX40, P22801
      UniProtKB/TrEMBL
      A6ZKM8, A6ZR58, B3LNK6, B3LRM0, B5VHM8, C8Z3S1, G2W8T8, G2WD21, N1P719
      Conserved Domains (1) summary
      PTZ00148
      Location:1 → 200
      PTZ00148; 40S ribosomal protein S8; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX39.1
    P0CX40.1

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