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    MRPL8 mitochondrial 54S ribosomal protein YmL8 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853382, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRPL8
    Official Full Name
    mitochondrial 54S ribosomal protein YmL8
    Primary source
    SGD:S000003599
    Locus tag
    YJL063C
    See related
    AllianceGenome:SGD:S000003599; FungiDB:YJL063C; VEuPathDB:YJL063C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    bL17m; HRD238
    Summary
    A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL17 (mitochondrial ribosomal protein L17). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRPL8 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (315759..316475, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Mpm1p Neighboring gene Dls1p Neighboring gene Coa3p Neighboring gene mannose-ethanolamine phosphotransferase LAS21

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of nuclear genes for two mitochondrial ribosomal proteins in Saccharomyces cerevisiae. Kitakawa M, et al. Nucleic Acids Res, 1990 Mar 25. PMID 2183197, Free PMC Article
    2. Mitochondrial transport of mitoribosomal proteins, YmL8 and YmL20, in Saccharomyces cerevisiae. Matsushita Y, et al. Eur J Biochem, 1993 Jun 1. PMID 8513807
    3. DPC29 promotes post-initiation mitochondrial translation in Saccharomyces cerevisiae. Hubble KA, et al. Nucleic Acids Res, 2023 Feb 22. PMID 36620885, Free PMC Article
    4. Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, et al. Science, 2014 Mar 28. PMID 24675956, Free PMC Article
    5. Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components. Gan X, et al. Eur J Biochem, 2002 Nov. PMID 12392552

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL8
    NP_012472.1
    • Mitochondrial ribosomal protein of the large subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      315759..316475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181496.1 → NP_012472.1  TPA: mitochondrial 54S ribosomal protein YmL8 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012472.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWB8, P22353
      UniProtKB/TrEMBL
      A6ZPQ8, B3LQ46, B5VLB3, C7GR48, C8ZBF0, G2WGV2, N1P1A5
      Conserved Domains (2) summary
      TIGR00059
      Location:7 → 127
      L17; ribosomal protein L17
      pfam18502
      Location:129 → 238
      Mrpl_C; 54S ribosomal protein L8 C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P22353.4

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