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    RGL1 Rgl1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856039, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RGL1
    Official Full Name
    Rgl1p
    Primary source
    SGD:S000005987
    Locus tag
    YPL066W
    See related
    AllianceGenome:SGD:S000005987; FungiDB:YPL066W; VEuPathDB:YPL066W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in protein localization to bud neck. Located in cellular bud neck and cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RGL1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (426233..427672)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Htc1p Neighboring gene ESCRT-I subunit protein VPS28 Neighboring gene putative peptidylprolyl isomerase CWC27

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A cell separation checkpoint that enforces the proper order of late cytokinetic events. Brace JL, et al. J Cell Biol, 2019 Jan 7. PMID 30455324, Free PMC Article
    2. Systematic screen for human disease genes in yeast. Steinmetz LM, et al. Nat Genet, 2002 Aug. PMID 12134146
    3. Functional specialisation of yeast Rho1 GTP exchange factors. Krause SA, et al. J Cell Sci, 2012 Jun 1. PMID 22344253
    4. An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. Lesage G, et al. BMC Genet, 2005 Feb 16. PMID 15715908, Free PMC Article
    5. A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae. McKinney JS, et al. BMC Genomics, 2013 Apr 15. PMID 23586741, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in division septum assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to bud neck IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein localization to bud neck IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cellular bud neck HDA PubMed 
    located_in cytoplasm HDA PubMed 
    is_active_in division septum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Rgl1p
    NP_015259.1
    • Regulator of Rho1p signaling, cofactor of Tus1p; required for the localization of Tus1p during all phases of cytokinesis; green fluorescent protein (GFP)-fusion protein localizes to the bud neck and cytoplasm; null mutant is viable and exhibits growth defect on a non-fermentable (respiratory) carbon source

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      426233..427672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183880.1 → NP_015259.1  TPA: Rgl1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015259.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3U9, Q12194
      UniProtKB/TrEMBL
      G2WPB4, N1NW44
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12194.1

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