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    SNZ2 pyridoxine biosynthesis protein SNZ2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855383, updated on 9-Dec-2024

    Summary

    Official Symbol
    SNZ2
    Official Full Name
    pyridoxine biosynthesis protein SNZ2
    Primary source
    SGD:S000005277
    Locus tag
    YNL333W
    See related
    AllianceGenome:SGD:S000005277; FungiDB:YNL333W; VEuPathDB:YNL333W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable GMP synthase (glutamine-hydrolyzing) activity and amine-lyase activity. Involved in pyridoxine biosynthetic process and thiamine biosynthetic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See SNZ2 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (13267..14163)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene cyanamide hydratase Neighboring gene putative pyridoxal 5'-phosphate synthase Neighboring gene 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase Neighboring gene putative aryl-alcohol dehydrogenase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables GMP synthase (glutamine-hydrolyzing) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables amine-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in GMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in amino acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in organic hydroxy compound biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pyridoxal phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in pyridoxal phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pyridoxine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in pyridoxine biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in pyridoxine biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in thiamine biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in vitamin B6 biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vitamin B6 biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    pyridoxine biosynthesis protein SNZ2
    NP_014066.1
    • Protein involved in thiamine and pyridoxine biosynthesis; member of a stationary phase-induced gene family where transcriptional induction precedes the diauxic shift; induced in the absence of thiamin in a Thi2/3p-dependent manner and repressed in its presence; forms a co-regulated gene pair with SNO2; interacts with Thi11p; paralog of SNZ1 and SNZ3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      13267..14163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183171.1NP_014066.1  TPA: pyridoxine biosynthesis protein SNZ2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014066.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0L4, P53824
      UniProtKB/TrEMBL
      B3LPG5, B5VQ90, C8ZBV7
      Conserved Domains (1) summary
      TIGR00343
      Location:6298
      TIGR00343; pyridoxal 5'-phosphate synthase, synthase subunit Pdx1