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    CUB1 Cub1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855867, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CUB1
    Official Full Name
    Cub1p
    Primary source
    SGD:S000006181
    Locus tag
    YPL260W
    See related
    AllianceGenome:SGD:S000006181; FungiDB:YPL260W; VEuPathDB:YPL260W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CUB1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (49303..50958)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Kel3p Neighboring gene fumarase FUM1 Neighboring gene uncharacterized protein Neighboring gene Apm1p Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase. Budovskaya YV, et al. Proc Natl Acad Sci U S A, 2005 Sep 27. PMID 16172400, Free PMC Article
    2. Insight into the Antioxidant Effect of Fermented and Non-Fermented Spirulina Water and Ethanol Extracts at the Proteome Level Using a Yeast Cell Model. Masten Rutar J, et al. Antioxidants (Basel), 2021 Aug 27. PMID 34572998, Free PMC Article
    3. The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock. Garre E, et al. PLoS Genet, 2018 Jul. PMID 30059503, Free PMC Article
    4. Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Lin YY, et al. Cell, 2009 Mar 20. PMID 19303850, Free PMC Article
    5. Alterations in DNA replication and histone levels promote histone gene amplification in Saccharomyces cerevisiae. Libuda DE, et al. Genetics, 2010 Apr. PMID 20139344, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cub1p
    NP_015063.1
    • Conserved fungal gene linked to DNA repair and proteasome function; putative substrate of cAMP-dependent protein kinase (PKA); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YPL260W is not an essential gene; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      49303..50958
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184074.1 → NP_015063.1  TPA: Cub1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015063.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3A9, Q05760, Q08977, Q7LGU3
      UniProtKB/TrEMBL
      B3LKH2, C7GSG2, C8ZIB9, N1NX25
      Conserved Domains (1) summary
      pfam10303
      Location:209 → 372
      DUF2408; Protein of unknown function (DUF2408)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08977.1

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