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    Jrk jerky [ Mus musculus (house mouse) ]

    Gene ID: 16469, updated on 27-Nov-2024

    Summary

    Official Symbol
    Jrkprovided by MGI
    Official Full Name
    jerkyprovided by MGI
    Primary source
    MGI:MGI:106214
    See related
    Ensembl:ENSMUSG00000046380 AllianceGenome:MGI:106214
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Enables mRNA binding activity. Predicted to be involved in positive regulation of canonical Wnt signaling pathway. Located in cytoplasm and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; early conceptus; eye; and genitourinary system. Orthologous to human JRK (Jrk helix-turn-helix protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 4.1), ovary adult (RPKM 2.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Jrk in Genome Data Viewer
    Location:
    15 D3; 15 34.26 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (74574261..74581171, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (74702412..74709322, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene maestro heat-like repeat family member 4 Neighboring gene STARR-seq mESC enhancer starr_38988 Neighboring gene STARR-seq mESC enhancer starr_38991 Neighboring gene predicted gene, 32994 Neighboring gene activity regulated cytoskeletal-associated protein Neighboring gene STARR-seq mESC enhancer starr_38994 Neighboring gene RIKEN cDNA 4933427E11 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:74553786-74554003 Neighboring gene prostate stem cell antigen Neighboring gene thioesterase superfamily member 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT located_in ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008415.6NP_032441.4  jerky protein

      See identical proteins and their annotated locations for NP_032441.4

      Status: VALIDATED

      Source sequence(s)
      AC118022, AK168885
      Consensus CDS
      CCDS27524.1
      UniProtKB/Swiss-Prot
      Q60976
      UniProtKB/TrEMBL
      Q543Z9, Q8C995
      Related
      ENSMUSP00000051842.3, ENSMUST00000050234.4
      Conserved Domains (3) summary
      smart00674
      Location:83147
      CENPB; Putative DNA-binding domain in centromere protein B, mouse jerky and transposases
      pfam03184
      Location:213382
      DDE_1; DDE superfamily endonuclease
      pfam04218
      Location:1466
      CENP-B_N; CENP-B N-terminal DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      74574261..74581171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)