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    Avpr1b arginine vasopressin receptor 1B [ Mus musculus (house mouse) ]

    Gene ID: 26361, updated on 27-Nov-2024

    Summary

    Official Symbol
    Avpr1bprovided by MGI
    Official Full Name
    arginine vasopressin receptor 1Bprovided by MGI
    Primary source
    MGI:MGI:1347010
    See related
    Ensembl:ENSMUSG00000026432 AllianceGenome:MGI:1347010
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    VIBR; VPR3; AVPR3; V3/V1b; AVPR V3; AVPR V1b
    Summary
    Predicted to enable vasopressin receptor activity. Involved in regulation of blood pressure. Acts upstream of or within regulation of systemic arterial blood pressure by vasopressin. Predicted to be located in Golgi apparatus. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in autism spectrum disorder; bipolar disorder; and mood disorder. Orthologous to human AVPR1B (arginine vasopressin receptor 1B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Avpr1b in Genome Data Viewer
    Location:
    1 E4; 1 57.09 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (131526908..131539740)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (131599114..131612000)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene SLIT-ROBO Rho GTPase activating protein 2 Neighboring gene predicted gene, 53252 Neighboring gene STARR-seq mESC enhancer starr_02218 Neighboring gene STARR-positive B cell enhancer ABC_E23 Neighboring gene STARR-positive B cell enhancer ABC_E8941 Neighboring gene STARR-positive B cell enhancer ABC_E5798 Neighboring gene family with sequence similarity 72, member A Neighboring gene STARR-seq mESC enhancer starr_02220 Neighboring gene STARR-positive B cell enhancer ABC_E11085 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:133534791-133534974 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:133554451-133554634 Neighboring gene adaptor-related protein complex AP-1, sigma 3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_02223 Neighboring gene cathepsin E

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (7)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables vasopressin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables vasopressin receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables vasopressin receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in G protein-coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to hormone stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of arachidonate secretion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of arachidonate secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of inositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of inositol phosphate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of phospholipase A2 activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of vasoconstriction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of blood pressure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of systemic arterial blood pressure by vasopressin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of systemic arterial blood pressure by vasopressin IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in symbiont entry into host cell IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in symbiont entry into host cell ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vasopressin V1b receptor
    Names
    V3/V1b pituitary vasopressin receptor
    antidiuretic hormone receptor 1b
    arginine vasopressin type 1b receptor
    vasopressin V3 receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011924.3NP_036054.1  vasopressin V1b receptor

      See identical proteins and their annotated locations for NP_036054.1

      Status: VALIDATED

      Source sequence(s)
      AC120217
      Consensus CDS
      CCDS35703.1
      UniProtKB/Swiss-Prot
      Q9WU02
      UniProtKB/TrEMBL
      Q9JLP2
      Related
      ENSMUSP00000027690.7, ENSMUST00000027690.7
      Conserved Domains (3) summary
      pfam00001
      Location:51335
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      pfam08983
      Location:359408
      DUF1856; Domain of unknown function (DUF1856)
      cl21561
      Location:41184
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      131526908..131539740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)