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    Zfp287 zinc finger protein 287 [ Mus musculus (house mouse) ]

    Gene ID: 170740, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp287provided by MGI
    Official Full Name
    zinc finger protein 287provided by MGI
    Primary source
    MGI:MGI:2176561
    See related
    Ensembl:ENSMUSG00000005267 AllianceGenome:MGI:2176561
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Skat2; SKAT-2; Znf287; mszf16; mszf74; zfp-287; B230333C16Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of DNA-templated transcription and regulation of cytokine production. Predicted to be active in nucleus. Is expressed in bladder; central nervous system; head; and ureter. Orthologous to human ZNF287 (zinc finger protein 287). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E18 (RPKM 1.9), CNS E14 (RPKM 1.8) and 21 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zfp287 in Genome Data Viewer
    Location:
    11 B2; 11 38.62 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (62583270..62622749, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (62692444..62731912, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 75A Neighboring gene leucine rich repeat containing 75A, opposite strand 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:62462281-62462390 Neighboring gene membrane magnesium transporter 2 Neighboring gene nuclear encoded tRNA trytophan 8 (anticodon CCA) Neighboring gene WD repeat and SOCS box-containing 2, pseudogene Neighboring gene zinc finger protein 286

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    zinc finger protein 287
    Names
    zinc finger protein SKAT-2
    zinc finger protein SKAT2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001382823.1NP_001369752.1  zinc finger protein 287 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL627097
      UniProtKB/TrEMBL
      Q3UZW0
      Related
      ENSMUSP00000121717.2, ENSMUST00000150336.8
      Conserved Domains (2) summary
      smart00349
      Location:166223
      KRAB; krueppel associated box
      pfam02023
      Location:39122
      SCAN; SCAN domain
    2. NM_001382824.1NP_001369753.1  zinc finger protein 287 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL627097
      UniProtKB/TrEMBL
      Q3UY44
      Related
      ENSMUSP00000117179.2, ENSMUST00000128370.2
      Conserved Domains (2) summary
      smart00349
      Location:166223
      KRAB; krueppel associated box
      pfam02023
      Location:39122
      SCAN; SCAN domain
    3. NM_133208.3NP_573471.2  zinc finger protein 287 isoform 1

      See identical proteins and their annotated locations for NP_573471.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AL627097
      Consensus CDS
      CCDS24830.1
      UniProtKB/Swiss-Prot
      Q8CDU3, Q9EQB9
      Related
      ENSMUSP00000005399.4, ENSMUST00000005399.10
      Conserved Domains (5) summary
      smart00349
      Location:166223
      KRAB; krueppel associated box
      COG5048
      Location:420753
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:424444
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:394416
      zf-C2H2; Zinc finger, C2H2 type
      cl02605
      Location:39138
      SCAN; SCAN oligomerization domain

    RNA

    1. NR_168576.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL627097

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      62583270..62622749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156368.1XP_036012261.1  zinc finger protein 287 isoform X2

      UniProtKB/TrEMBL
      Q3UZW0
      Conserved Domains (2) summary
      smart00349
      Location:166223
      KRAB; krueppel associated box
      pfam02023
      Location:39122
      SCAN; SCAN domain
    2. XM_036156369.1XP_036012262.1  zinc finger protein 287 isoform X2

      UniProtKB/TrEMBL
      Q3UZW0
      Conserved Domains (2) summary
      smart00349
      Location:166223
      KRAB; krueppel associated box
      pfam02023
      Location:39122
      SCAN; SCAN domain
    3. XM_036156367.1XP_036012260.1  zinc finger protein 287 isoform X1

      Conserved Domains (4) summary
      COG5048
      Location:238571
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:212234
      zf-C2H2; Zinc finger, C2H2 type
      cl02581
      Location:341
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    RNA

    1. XR_004936821.1 RNA Sequence

    2. XR_004936817.1 RNA Sequence

    3. XR_004936820.1 RNA Sequence

    4. XR_879531.4 RNA Sequence

    5. XR_004936819.1 RNA Sequence

    6. XR_004936818.1 RNA Sequence

    7. XR_879525.4 RNA Sequence

    8. XR_879527.4 RNA Sequence

    9. XR_004936811.1 RNA Sequence

    10. XR_004936810.1 RNA Sequence

    11. XR_004936812.1 RNA Sequence

    12. XR_001779891.3 RNA Sequence

    13. XR_001779892.3 RNA Sequence

    14. XR_004936809.1 RNA Sequence

    15. XR_004936807.1 RNA Sequence

    16. XR_004936808.1 RNA Sequence

    17. XR_004936816.1 RNA Sequence

    18. XR_004936814.1 RNA Sequence

    19. XR_004936815.1 RNA Sequence

    20. XR_004936813.1 RNA Sequence