Cfap91 cilia and flagella associated protein 91 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cfap91provided by MGI
Official Full Name: cilia and flagella associated protein 91provided by MGI
Primary source: MGI:MGI:2443598
See related: Ensembl:ENSMUSG00000022805 AllianceGenome:MGI:2443598
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Aat1; Maats1; Spata26; 4932425I24Rik
Summary: Predicted to be involved in axonemal central apparatus assembly; cilium movement; and spermatogenesis. Predicted to be located in axoneme and motile cilium. Predicted to be part of radial spoke stalk. Is expressed in choroid invagination; diencephalon roof plate; lung; and metencephalon part of 4th ventricle choroid plexus. Human ortholog(s) of this gene implicated in spermatogenic failure 51. Orthologous to human CFAP91 (cilia and flagella associated protein 91). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in testis adult (RPKM 9.6), placenta adult (RPKM 0.9) and 1 other tissue See more
Orthologs: human all
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Genomic context

Location:: 16 B3; 16 26.71 cM

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (38118116..38162222, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (38297754..38341860, complement)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in axonemal central apparatus assembly	ISO Inferred from Sequence Orthology more info
involved_in axonemal central apparatus assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in cilium movement	ISS Inferred from Sequence or Structural Similarity more info
involved_in spermatogenesis	ISO Inferred from Sequence Orthology more info
involved_in spermatogenesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in axoneme	ISS Inferred from Sequence or Structural Similarity more info
is_active_in cellular_component	ND No biological Data available more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in motile cilium	ISS Inferred from Sequence or Structural Similarity more info
part_of radial spoke stalk	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: cilia- and flagella-associated protein 91

Names: AAT-1; AMY-1-associating protein expressed in testis 1 homolog; MYCBP-associated, testis expressed 1; MYCBP/AMY-1-associated testis-expressed protein 1; protein MAATS1; spermatogenesis associated 26

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001081025.1 → NP_001074494.1 cilia- and flagella-associated protein 91

See identical proteins and their annotated locations for NP_001074494.1

Status: PROVISIONAL

Source sequence(s)

AC154809

Consensus CDS

CCDS37341.1

UniProtKB/Swiss-Prot

E9PZ32, E9QND1, Q8BRC6

Related

ENSMUSP00000023501.9, ENSMUST00000023501.16

Conserved Domains (1) summary

pfam14738
Location:190 → 342

PaaSYMP; Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000082.7 Reference GRCm39 C57BL/6J

Range

38118116..38162222 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006522245.3 → XP_006522308.1 cilia- and flagella-associated protein 91 isoform X1

Conserved Domains (2) summary

pfam14738
Location:71 → 223

PaaSYMP; Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1

pfam17380
Location:398 → 571

DUF5401; Family of unknown function (DUF5401)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_177104.1: Suppressed sequence

Description

NM_177104.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.