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    Zbtb47 zinc finger and BTB domain containing 47 [ Mus musculus (house mouse) ]

    Gene ID: 270210, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zbtb47provided by MGI
    Official Full Name
    zinc finger and BTB domain containing 47provided by MGI
    Primary source
    MGI:MGI:2670992
    See related
    Ensembl:ENSMUSG00000013419 AllianceGenome:MGI:2670992
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp651; 4732420M22Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZBTB47 (zinc finger and BTB domain containing 47). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 20.0), heart adult (RPKM 16.7) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zbtb47 in Genome Data Viewer
    Location:
    9 F4; 9 72.6 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (121588210..121600808)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (121759319..121771742)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1400 Neighboring gene SS18, nBAF chromatin remodeling complex subunit like 2 Neighboring gene STARR-positive B cell enhancer ABC_E10593 Neighboring gene natural killer tumor recognition sequence Neighboring gene RIKEN cDNA E530011L22 gene Neighboring gene STARR-positive B cell enhancer ABC_E6812 Neighboring gene kelch-like 40 Neighboring gene hedgehog acyltransferase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 47
    Names
    zinc finger protein 651

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166644.1 → NP_001160116.1  zinc finger and BTB domain-containing protein 47

      Status: VALIDATED

      Source sequence(s)
      AC165080
      Consensus CDS
      CCDS52968.1
      UniProtKB/TrEMBL
      E9PZ11
      Related
      ENSMUSP00000091286.4, ENSMUST00000093772.4
      Conserved Domains (6) summary
      smart00225
      Location:46 → 141
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:641 → 690
      COG5048; FOG: Zn-finger [General function prediction only]
      TIGR04104
      Location:588 → 632
      cxxc_20_cxxc; cxxc_20_cxxc protein
      sd00017
      Location:589 → 609
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:32 → 138
      BTB; BTB/POZ domain
      pfam13465
      Location:657 → 680
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      121588210..121600808
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512145.5 → XP_006512208.1  zinc finger and BTB domain-containing protein 47 isoform X1

      Conserved Domains (5) summary
      PLN03086
      Location:405 → 479
      PLN03086; PRLI-interacting factor K; Provisional
      COG5048
      Location:613 → 662
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:555 → 638
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:561 → 581
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18231
      Location:1 → 114
      BTB_POZ_ZBTB47_ZNF651; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 47 (ZBTB47)

    2. XM_006512146.2 → XP_006512209.1  zinc finger and BTB domain-containing protein 47 isoform X2

      UniProtKB/TrEMBL
      A0A1L1STM6
      Conserved Domains (3) summary
      PLN03086
      Location:433 → 507
      PLN03086; PRLI-interacting factor K; Provisional
      sd00017
      Location:476 → 495
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18231
      Location:29 → 142
      BTB_POZ_ZBTB47_ZNF651; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 47 (ZBTB47)

    RNA

    1. XR_001778915.2 RNA Sequence

    2. XR_004935442.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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