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    Prp2 proline rich protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 83380, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prp2provided by MGI
    Official Full Name
    proline rich protein 2provided by MGI
    Primary source
    MGI:MGI:1932491
    See related
    Ensembl:ENSMUSG00000058295 AllianceGenome:MGI:1932491
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MP14
    Summary
    This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The expression of this gene is dramatically induced in the parotid and submandibular glands of mice by beta-adrenergic stimulation. The encoded protein serves an important dental function by protecting mice against toxic dietary polyphenols such as tannins and influence the visco-elastic properties of the mucus. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 6. [provided by RefSeq, Nov 2015]
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    Genomic context

    See Prp2 in Genome Data Viewer
    Location:
    6 G1; 6 64.03 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (132572874..132577665)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (132595911..132600702)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 18326 Neighboring gene STARR-seq mESC enhancer starr_17509 Neighboring gene STARR-seq mESC enhancer starr_17510 Neighboring gene STARR-seq mESC enhancer starr_17511 Neighboring gene STARR-seq mESC enhancer starr_17512 Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene RIKEN cDNA A630073D07 gene Neighboring gene taste receptor, type 2, member 120

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    proline-rich protein 2
    Names
    proline-rich protein MP-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031499.3NP_113687.2  proline-rich protein 2 precursor

      See identical proteins and their annotated locations for NP_113687.2

      Status: REVIEWED

      Source sequence(s)
      AC124523
      Consensus CDS
      CCDS51931.1
      UniProtKB/TrEMBL
      F8VPU9
      Related
      ENSMUSP00000075435.4, ENSMUST00000076061.4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      132572874..132577665
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)