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    PF3D7_1029600 adenosine deaminase [ Plasmodium falciparum 3D7 ]

    Gene ID: 810446, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1029600
    Gene description
    adenosine deaminase
    Locus tag
    PF3D7_1029600
    See related
    PlasmoDB:PF3D7_1029600; VEuPathDB:PF3D7_1029600
    Gene type
    protein coding
    RNA name
    adenosine deaminase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1029600 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    1
    Sequence:
    Chromosome: 10; NC_037281.1 (1206302..1207405)

    Chromosome 10 - NC_037281.1Genomic Context describing neighboring genes Neighboring gene LEM3/CDC50 family protein, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene heptatricopeptide repeat and RAP domain-containing protein, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037281.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of Plasmodium falciparum adenosine deaminase reveals a novel binding pocket for inosine. Jaruwat A, et al. Arch Biochem Biophys, 2019 May 30. PMID 31002765
    2. Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins. Ting LM, et al. J Biol Chem, 2005 Mar 11. PMID 15576366
    3. Mapping the genome of Plasmodium falciparum on the drug-like chemical space reveals novel anti-malarial targets and potential drug leads. Jensen K, et al. Mol Biosyst, 2012 Jun. PMID 22446744
    4. A network-based approach reveals novel invasion and Maurer's clefts-related proteins in Plasmodium falciparum. Das D, et al. Mol Omics, 2019 Dec 2. PMID 31631203
    5. A protein interaction network of the malaria parasite Plasmodium falciparum. LaCount DJ, et al. Nature, 2005 Nov 3. PMID 16267556

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables adenosine deaminase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to xenobiotic stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Maurer's cleft RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenosine deaminase
    XP_001347573.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037281.1 Reference assembly

      Range
      1206302..1207405
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001347537.1 → XP_001347573.1  adenosine deaminase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001347573.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q8IJA9
      UniProtKB/TrEMBL
      A0A024V6D2, A0A024VQ13, A0A024W5Q5, A0A024WPY9, A0A024X7D0, A0A0L0CWX5, A0A0L1IBV7, A0A0L7K895, A0A0L7M7L7, Q86GS5, W4IFN3, W4J2V5, W7FBE1, W7FHR1, W7JBN9, W7K4P1
      Conserved Domains (1) summary
      PTZ00124
      Location:6 → 367
      PTZ00124; adenosine deaminase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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