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    PF3D7_1117500 tyrosine--tRNA ligase [ Plasmodium falciparum 3D7 ]

    Gene ID: 810728, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1117500
    Gene description
    tyrosine--tRNA ligase
    Locus tag
    PF3D7_1117500
    See related
    PlasmoDB:PF3D7_1117500; VEuPathDB:PF3D7_1117500
    Gene type
    protein coding
    RNA name
    tyrosine--tRNA ligase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1117500 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    1
    Sequence:
    Chromosome: 11; NC_037282.1 (666037..667722, complement)

    Chromosome 11 - NC_037282.1Genomic Context describing neighboring genes Neighboring gene conserved protein, unknown function Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene peptidyl-tRNA hydrolase ICT1 Neighboring gene GTP-binding nuclear protein RAN/TC4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037282.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasmodium apicoplast tyrosyl-tRNA synthetase recognizes an unusual, simplified identity set in cognate tRNATyr. Cela M, et al. PLoS One, 2018. PMID 30592748, Free PMC Article
    2. A genomic glimpse of aminoacyl-tRNA synthetases in malaria parasite Plasmodium falciparum. Bhatt TK, et al. BMC Genomics, 2009 Dec 31. PMID 20042123, Free PMC Article
    3. Malaria parasite tyrosyl-tRNA synthetase secretion triggers pro-inflammatory responses. Bhatt TK, et al. Nat Commun, 2011 Nov 8. PMID 22068597
    4. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article
    5. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables tyrosine-tRNA ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within tyrosyl-tRNA aminoacylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apicoplast HDA PubMed 
    located_in apicoplast RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine--tRNA ligase
    XP_001347852.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037282.1 Reference assembly

      Range
      666037..667722 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001347816.2 → XP_001347852.2  tyrosine--tRNA ligase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001347852.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024UZ38, A0A024W746, A0A024X6B1, A0A2I0C0M7, Q8IIJ2, W4ITX3, W7EZ40, W7FXE3, W7JAV8
      Conserved Domains (1) summary
      PRK05912
      Location:46 → 553
      PRK05912; tyrosyl-tRNA synthetase; Validated
    Nucleotide Protein
    Heading Accession and Version

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