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    PF3D7_1437900 HSP40, subfamily A [ Plasmodium falciparum 3D7 ]

    Gene ID: 811941, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1437900
    Gene description
    HSP40, subfamily A
    Locus tag
    PF3D7_1437900
    See related
    PlasmoDB:PF3D7_1437900; VEuPathDB:PF3D7_1437900
    Gene type
    protein coding
    RNA name
    HSP40, subfamily A
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1437900 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    2
    Sequence:
    Chromosome: 14; NC_037283.1 (1533329..1534947)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene succinyl-CoA ligase, putative Neighboring gene trafficking protein particle complex subunit 5, putative Neighboring gene eukaryotic translation initiation factor eIF2A, putative Neighboring gene translocation protein SEC62, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein Prenylation and Hsp40 in Thermotolerance of Plasmodium falciparum Malaria Parasites. Mathews ES, et al. mBio, 2021 Jun 29. PMID 34182772, Free PMC Article
    2. Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock. Botha M, et al. Cell Stress Chaperones, 2011 Jul. PMID 21191678, Free PMC Article
    3. Functional Characterization of the m(6)A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite. Sinha A, et al. mBio, 2021 Apr 27. PMID 33906926, Free PMC Article
    4. Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. Briquet S, et al. PLoS One, 2018. PMID 30379851, Free PMC Article
    5. A protein interaction network of the malaria parasite Plasmodium falciparum. LaCount DJ, et al. Nature, 2005 Nov 3. PMID 16267556

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Protein Prenylation and Hsp40 in Thermotolerance of Plasmodium falciparum Malaria Parasites.
      Title: Protein Prenylation and Hsp40 in Thermotolerance of Plasmodium falciparum Malaria Parasites.
    2. these data represent the first cellular and biochemical evidence for a PfHsp70-PfHsp40 partnership in the malaria parasite.
      Title: Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables Hsp70 protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA binding HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to heat IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in host cell plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    HSP40, subfamily A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      1533329..1534947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348497.1 → XP_001348533.1  HSP40, subfamily A [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348533.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V030, A0A024VZ21, A0A024WIB1, A0A024WYT8, A0A0L1ID28, A0A0L7K592, A0A0L7M1K5, A0A2I0C234, Q8IL88, W4I910, W4IVL1, W7EU32, W7JQM9, W7K7J8
      Conserved Domains (1) summary
      PTZ00037
      Location:1 → 424
      PTZ00037; DnaJ_C chaperone protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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