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    PF3D7_1443700 dephospho-CoA kinase, putative [ Plasmodium falciparum 3D7 ]

    Gene ID: 811997, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1443700
    Gene description
    dephospho-CoA kinase, putative
    Locus tag
    PF3D7_1443700
    See related
    PlasmoDB:PF3D7_1443700; VEuPathDB:PF3D7_1443700
    Gene type
    protein coding
    RNA name
    dephospho-CoA kinase, putative
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1443700 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    2
    Sequence:
    Chromosome: 14; NC_037283.1 (1791911..1793004, complement)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene poly(A)-specific ribonuclease PARN, putative Neighboring gene gamma-tubulin complex component, putative Neighboring gene pre-mRNA-splicing factor CWC24, putative Neighboring gene heat shock protein 90, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dephospho-CoA kinase, a nuclear-encoded apicoplast protein, remains active and essential after Plasmodium falciparum apicoplast disruption. Swift RP, et al. EMBO J, 2021 Aug 16. PMID 34031901, Free PMC Article
    2. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article
    3. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Dephospho-CoA kinase, a nuclear-encoded apicoplast protein, remains active and essential after Plasmodium falciparum apicoplast disruption.
      Title: Dephospho-CoA kinase, a nuclear-encoded apicoplast protein, remains active and essential after Plasmodium falciparum apicoplast disruption.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables dephospho-CoA kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within coenzyme A biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apicoplast HDA PubMed 
    located_in apicoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dephospho-CoA kinase, putative
    XP_001348589.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      1791911..1793004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348553.1 → XP_001348589.1  dephospho-CoA kinase, putative [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348589.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V083, A0A024VKQ0, A0A024W184, A0A024WJB9, A0A024WYX8, A0A0L7KA27, Q8IL34, W4I9M2, W4IXL1, W7FE78, W7FM72, W7JQL1, W7JWP0
      Conserved Domains (1) summary
      cd02022
      Location:74 → 256
      DPCK; Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.
    Nucleotide Protein
    Heading Accession and Version

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