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    PF3D7_1451800 sortilin [ Plasmodium falciparum 3D7 ]

    Gene ID: 812075, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1451800
    Gene description
    sortilin
    Locus tag
    PF3D7_1451800
    See related
    PlasmoDB:PF3D7_1451800; VEuPathDB:PF3D7_1451800
    Gene type
    protein coding
    RNA name
    sortilin
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1451800 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    4
    Sequence:
    Chromosome: 14; NC_037283.1 (2123461..2126599)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene LCCL domain-containing protein Neighboring gene calcineurin subunit B Neighboring gene ribosome biogenesis protein TSR1, putative Neighboring gene rhoptry neck protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The malaria parasite Plasmodium falciparum Sortilin is essential for merozoite formation and apical complex biogenesis. Hallée S, et al. Cell Microbiol, 2018 Aug. PMID 29582546
    2. Evidence that the Plasmodium falciparum Protein Sortilin Potentially Acts as an Escorter for the Trafficking of the Rhoptry-Associated Membrane Antigen to the Rhoptries. Hallée S, et al. mSphere, 2018 Jan-Feb. PMID 29299530, Free PMC Article
    3. Evidence for a Golgi-to-endosome protein sorting pathway in Plasmodium falciparum. Krai P, et al. PLoS One, 2014. PMID 24587025, Free PMC Article
    4. A protein interaction network of the malaria parasite Plasmodium falciparum. LaCount DJ, et al. Nature, 2005 Nov 3. PMID 16267556
    5. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cis-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sortilin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      2123461..2126599
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348631.1 → XP_001348667.1  sortilin [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348667.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V1E6, A0A024WZ58, A0A0L0CRY9, A0A0L1I798, A0A0L7KHJ9, A0A2I0C2N5, Q8IKV8, W4I7S5, W4IVW8, W7F0E0, W7FB27, W7JG25
      Conserved Domains (2) summary
      pfam15901
      Location:602 → 760
      Sortilin_C; Sortilin, neurotensin receptor 3, C-terminal
      pfam15902
      Location:98 → 599
      Sortilin-Vps10; Sortilin, neurotensin receptor 3,
    Nucleotide Protein
    Heading Accession and Version

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