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    PF3D7_0305600 DNA-(apurinic or apyrimidinic site) lyase, putative [ Plasmodium falciparum 3D7 ]

    Gene ID: 814374, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_0305600
    Gene description
    DNA-(apurinic or apyrimidinic site) lyase, putative
    Locus tag
    PF3D7_0305600
    See related
    PlasmoDB:PF3D7_0305600; VEuPathDB:PF3D7_0305600
    Gene type
    protein coding
    RNA name
    DNA-(apurinic or apyrimidinic site) lyase, putative
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_0305600 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_000521.4 (275864..277717, complement)

    Chromosome 3 - NC_000521.4Genomic Context describing neighboring genes Neighboring gene conserved protein, unknown function Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene ubiquitin-conjugating enzyme E2, putative Neighboring gene P-loop containing nucleoside triphosphate hydrolase, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000521.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasmodium Ape1 is a multifunctional enzyme in mitochondrial base excision repair and is required for efficient transition from liver to blood stage infection. Verma N, et al. DNA Repair (Amst), 2021 May. PMID 33743509
    2. Identification and characterization of DNA endonucleases in Plasmodium falciparum 3D7 clone. Jiang N, et al. Malar J, 2018 Jun 18. PMID 29914511, Free PMC Article
    3. The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum. Bowman S, et al. Nature, 1999 Aug 5. PMID 10448855
    4. Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. Briquet S, et al. PLoS One, 2018. PMID 30379851, Free PMC Article
    5. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables 3'-5' exonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-(apurinic or apyrimidinic site) endonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA nuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within symbiont entry into host IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-(apurinic or apyrimidinic site) lyase, putative
    XP_001351132.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000521.4 Reference assembly

      Range
      275864..277717 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001351096.1 → XP_001351132.1  DNA-(apurinic or apyrimidinic site) lyase, putative [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001351132.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O97240
      UniProtKB/TrEMBL
      A0A024WY13, W7FEJ7, W7K0G0
      Conserved Domains (1) summary
      cl00490
      Location:280 → 614
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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