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    PF3D7_1232000 phenylalanine--tRNA ligase [ Plasmodium falciparum 3D7 ]

    Gene ID: 811360, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1232000
    Gene description
    phenylalanine--tRNA ligase
    Locus tag
    PF3D7_1232000
    See related
    PlasmoDB:PF3D7_1232000; VEuPathDB:PF3D7_1232000
    Gene type
    protein coding
    RNA name
    phenylalanine--tRNA ligase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1232000 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    2
    Sequence:
    Chromosome: 12; NC_037284.1 (1325484..1327339, complement)

    Chromosome 12 - NC_037284.1Genomic Context describing neighboring genes Neighboring gene asparagine-rich protein, putative Neighboring gene WD repeat-containing protein, putative Neighboring gene 60 kDa chaperonin Neighboring gene dihydrolipoyl dehydrogenase, mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037284.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasmodium falciparum mitochondria import tRNAs along with an active phenylalanyl-tRNA synthetase. Sharma A, et al. Biochem J, 2015 Feb 1. PMID 25391660
    2. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article
    3. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Component Evidence Code Pubs
    located_in apicoplast HDA PubMed 
    located_in apicoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phenylalanine--tRNA ligase
    XP_001350714.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037284.1 Reference assembly

      Range
      1325484..1327339 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001350678.2 → XP_001350714.2  phenylalanine--tRNA ligase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001350714.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0L1I6H0, A0A2I0BYY3, Q8I5A1
      Conserved Domains (2) summary
      cl00268
      Location:204 → 338
      class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...
      cl29820
      Location:463 → 556
      FDX-ACB; Ferredoxin-fold anticodon binding domain
    Nucleotide Protein
    Heading Accession and Version

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