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    MTC1 Mtc1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853319, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MTC1
    Official Full Name
    Mtc1p
    Primary source
    SGD:S000003659
    Locus tag
    YJL123C
    See related
    AllianceGenome:SGD:S000003659; FungiDB:YJL123C; VEuPathDB:YJL123C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MTC1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (188004..189440, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene tRNA 1-methyladenosine methyltransferase subunit GCD14 Neighboring gene Lsm1p Neighboring gene Alb1p Neighboring gene ribulose-phosphate 3-epimerase RPE1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The filamentous growth MAPK Pathway Responds to Glucose Starvation Through the Mig1/2 transcriptional repressors in Saccharomyces cerevisiae. Karunanithi S, et al. Genetics, 2012 Nov. PMID 22904036, Free PMC Article
    2. Distinct roles of spindle checkpoint proteins in meiosis. Mukherjee A, et al. Curr Biol, 2024 Aug 19. PMID 39079532
    3. Brr2p carboxy-terminal Sec63 domain modulates Prp16 splicing RNA helicase. Cordin O, et al. Nucleic Acids Res, 2014 Dec 16. PMID 25428373, Free PMC Article
    4. The DNA damage response pathway contributes to the stability of chromosome III derivatives lacking efficient replicators. Theis JF, et al. PLoS Genet, 2010 Dec 2. PMID 21151954, Free PMC Article
    5. Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Fleischer TC, et al. Genes Dev, 2006 May 15. PMID 16702403, Free PMC Article

    See all (59) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in COPI-coated vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus HDA PubMed 
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Mtc1p
    NP_012412.1
    • hypothetical protein that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); mtc1 is synthetically lethal with cdc13-1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      188004..189440 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181556.1 → NP_012412.1  TPA: Mtc1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012412.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW63, P47018
      UniProtKB/TrEMBL
      A6ZQK8, N1P939
      Conserved Domains (1) summary
      pfam10310
      Location:14 → 477
      DUF5427; Family of unknown function (DUF5427)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47018.1

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