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    MPH3 alpha-glucoside permease [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853625, updated on 2-Nov-2024

    Summary

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    Official Symbol
    MPH3
    Official Full Name
    alpha-glucoside permease
    Primary source
    SGD:S000003921
    Locus tag
    YJR160C
    See related
    AllianceGenome:SGD:S000003921; FungiDB:YJR160C; VEuPathDB:YJR160C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable carbohydrate:proton symporter activity and maltose transmembrane transporter activity. Involved in carbohydrate transport. Located in cell periphery and fungal-type vacuole. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See MPH3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (738008..739816, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene hexose transporter HXT16 Neighboring gene L-iditol 2-dehydrogenase SOR1 Neighboring gene Cos5p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the putative maltose transporters encoded by YDL247w and YJR160c. Day RE, et al. Yeast, 2002 Sep 15. PMID 12210897
    2. Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Brown CA, et al. Curr Biol, 2010 May 25. PMID 20471265, Free PMC Article
    3. A Novel Sterol-Signaling Pathway Governs Azole Antifungal Drug Resistance and Hypoxic Gene Repression in Saccharomyces cerevisiae. Serratore ND, et al. Genetics, 2018 Mar. PMID 29263028, Free PMC Article
    4. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. Galibert F, et al. EMBO J, 1996 May 1. PMID 8641269, Free PMC Article
    5. Exploring the yeast acetylome using functional genomics. Kaluarachchi Duffy S, et al. Cell, 2012 May 11. PMID 22579291, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables carbohydrate:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables maltose transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in carbohydrate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in maltose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in maltose transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in fungal-type vacuole HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    alpha-glucoside permease
    NP_012694.1
    • Alpha-glucoside permease; transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      738008..739816 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181818.1 → NP_012694.1  TPA: alpha-glucoside permease [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012694.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B5VF36, D6VWX8, P0CE00
      UniProtKB/TrEMBL
      N1P3Z4
      Conserved Domains (1) summary
      TIGR00879
      Location:72 → 556
      SP; MFS transporter, sugar porter (SP) family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CE00.1

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